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GLUCOSYLCERAMIDASE

Known as: Lysosomal Glucocerebrosidase, beta Glucocerebrosidase, D-Glucosyl-N-Acylsphingosine Glucohydrolase 
A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high… 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Mutations in the glucocerebrosidase gene (GBA) represent a significant risk factor for developing Parkinson disease (PD). We… 
Review
2009
Review
2009
Research in Parkinson's disease (PD) genetics has been extremely prolific over the past decade. More than 13 loci and 9 genes… 
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Recent studies indicate an increased frequency of mutations in the gene encoding glucocerebrosidase (GBA), a… 
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Review
2009
Review
2009
Mutations in the glucocerebrosidase gene (GBA) are associated with Gaucher's disease, the most common lysosomal storage disorder… 
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Review
2009
Review
2009
Parkinson's disease is a common progressive bradykinetic disorder that can be accurately diagnosed. It is characterised by the… 
Review
2008
Review
2008
Gaucher disease (GD) is an autosomal recessive disorder caused by the deficiency of glucocerebrosidase, a lysosomal enzyme that… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND A clinical association has been reported between type 1 Gaucher's disease, which is caused by a glucocerebrosidase… 
Highly Cited
2000
Highly Cited
2000
BACKGROUND Current treatment for Gaucher's disease involves administration of intravenous glucocerebrosidase to degrade… 
Review
2000
Review
2000
Plants have considerable potential for the production of biopharmaceutical proteins and peptides because they are easily… 
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Highly Cited
1994
Highly Cited
1994
Gaucher disease (GD; glucosylceramidosis) is caused by a deficient activity of the enzyme glucocerebrosidase (GC). Clinical… 
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