GLUCOSYLCERAMIDASE

Known as: Lysosomal Glucocerebrosidase, beta Glucocerebrosidase, D-Glucosyl-N-Acylsphingosine Glucohydrolase 
A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high… (More)
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Research in Parkinson's disease (PD) genetics has been extremely prolific over the past decade. More than 13 loci and 9 genes… (More)
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Highly Cited
2007
Highly Cited
2007
Gaucher's disease, a lysosomal storage disorder caused by mutations in the gene encoding glucocerebrosidase (GCD), is currently… (More)
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Review
2006
Review
2006
Parkinson's disease is a common progressive bradykinetic disorder that can be accurately diagnosed. It is characterised by the… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND A clinical association has been reported between type 1 Gaucher's disease, which is caused by a glucocerebrosidase… (More)
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Highly Cited
2004
Highly Cited
2004
Recent studies showing an association between glucocerebrosidase deficiency and parkinsonism in Gaucher disease prompted an… (More)
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Highly Cited
2003
Highly Cited
2003
Among the phenotypes associated with Gaucher disease, the deficiency of glucocerebrosidase, are rare patients with early onset… (More)
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Review
2000
Review
2000
Plants have considerable potential for the production of biopharmaceutical proteins and peptides because they are easily… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Current treatment for Gaucher's disease involves administration of intravenous glucocerebrosidase to degrade… (More)
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Highly Cited
1995
Highly Cited
1995
Gaucher disease, an inborn error of glycosphingolipid metabolism, is the most frequent lysosomal storage disease [1]. Non… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND AND METHODS Gaucher's disease, the most prevalent of the sphingolipid storage disorders, is caused by a deficiency of… (More)
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