ilimaquinone

TRAIL induces apoptosis in a variety of tumor cells. However, development of resistance to TRAIL is a major obstacle to more… Expand

Protein kinase D (PKD) is a novel family of serine/threonine kinases targeted by the second messenger diacylglycerol. It has been… Expand

Although organelles such as the endoplasmic reticulum and Golgi apparatus are highly compartmentalized, these organelles are… Expand

The marine organisms produce many metabolic substances with numerous pharmacological activities. It has been suggested that… Expand

In order to combat the human immunodeficiency virus (HIV), diverse strategies have been developed to research on compounds which… Expand

The chancroid bacterium Haemophilus ducreyi produces a toxin (HdCDT) which is a member of the recently discovered family of… Expand

Translocation of ricin A chain to the cytosol has been proposed to take place from the endoplasmic reticulum (ER), but attempts… Expand

Autocrine motility factor receptor (AMF-R) is a marker for a distinct smooth membranous tubule. Ilimaquinone (IQ) is a sea sponge… Expand

Ilimaquinone (IQ), a metabolite from sea sponges, has been shown to cause the breakdown of Golgi membranes into small vesicular… Expand

We have identified a novel natural metabolite, ilimaquinone (IQ), from sea sponges that causes Golgi membranes to break down… Expand