ilimaquinone

TRAIL induces apoptosis in a variety of tumor cells. However, development of resistance to TRAIL is a major obstacle to more… (More)

Although organelles such as the endoplasmic reticulum and Golgi apparatus are highly compartmentalized, these organelles are… (More)

The marine organisms produce many metabolic substances with numerous pharmacological activities. It has been suggested that… (More)

BACKGROUND The marine sponge metabolite (-)-ilimaquinone has antimicrobial, anti-HIV, anti-inflammatory and antimitotic… (More)

The total synthesis of (-)-ilimaquinone, a metabolite isolated from sea sponges, is described. The key step of the synthesis is… (More)

The marine sponge metabolite ilimaquinone (1) displays a broad range of biological activities. To better understand the effects… (More)

Translocation of ricin A chain to the cytosol has been proposed to take place from the endoplasmic reticulum (ER), but attempts… (More)

Autocrine motility factor receptor (AMF-R) is a marker for a distinct smooth membranous tubule. Ilimaquinone (IQ) is a sea sponge… (More)

Ilimaquinone (IQ), a metabolite from sea sponges, has been shown to cause the breakdown of Golgi membranes into small vesicular… (More)

We have identified a novel natural metabolite, ilimaquinone (IQ), from sea sponges that causes Golgi membranes to break down… (More)