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ilimaquinone

National Institutes of Health

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Broader (2)

QuinonesSesquiterpenes

Papers overview

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2020
2020
Ilimaquinone Induces the Apoptotic Cell Death of Cancer Cells by Reducing Pyruvate Dehydrogenase Kinase 1 Activity
In cancer cells, aerobic glycolysis rather than oxidative phosphorylation (OxPhos) is generally preferred for the production of… 
2015
2015
Activation of p53 with Ilimaquinone and Ethylsmenoquinone, Marine Sponge Metabolites, Induces Apoptosis and Autophagy in Colon Cancer Cells
The tumor suppressor, p53, plays an essential role in the cellular response to stress through regulating the expression of genes… 
Highly Cited
2014
Highly Cited
2014
Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.
2000
2000
Reconstitution of the Golgi reassembly process in semi-intact MDCK cells.
1999
1999
Interactions of (-)-ilimaquinone with methylation enzymes: implications for vesicular-mediated secretion.
1997
1997
New Tools for Studying Vesicular-Mediated Protein Trafficking: Synthesis and Evaluation of Ilimaquinone Analogs in a Non-Radioisotope-Based Antisecretory Assay.
Structural variants of the marine sponge metabolite ilimaquinone, with comparable biological activity, have been prepared. These… 
1997
1997
Loss of Gap Junction Plaques and Inhibition of Intercellular Communication in Ilimaquinone-treated BICR-M1Rk and NRK Cells
Abstract. To examine the mechanism(s) and pathways of gap junction formation and removal a novel and reversible inhibitor of… 
1997
1997
New sesquiterpene hydroquinones from a Taiwanese marine sponge Polyfibrospongia australis.
Two new sesquiterpene hydroquinones, polyfibrospongols A (1) and B (2), were isolated from the Taiwanese marine sponge… 
1995
1995
Reconstitution of vesiculated Golgi membranes into stacks of cisternae: requirement of NSF in stack formation
We have developed an in vitro system to study the biochemical events in the fusion of ilimaquinone (IQ) induced vesiculated Golgi… 
Highly Cited
1993
Highly Cited
1993
Microtubule independent vesiculation of Golgi membranes and the reassembly of vesicles into Golgi stacks
We have recently shown that ilimaquinone (IQ) causes the breakdown of Golgi membranes into small vesicles (VGMs for vesiculated… 
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