Microtubule independent vesiculation of Golgi membranes and the reassembly of vesicles into Golgi stacks

@article{Veit1993MicrotubuleIV,
  title={Microtubule independent vesiculation of Golgi membranes and the reassembly of vesicles into Golgi stacks},
  author={B Veit and Jennifer K. Yucel and Vandana Malhotra},
  journal={The Journal of Cell Biology},
  year={1993},
  volume={122},
  pages={1197 - 1206}
}
We have recently shown that ilimaquinone (IQ) causes the breakdown of Golgi membranes into small vesicles (VGMs for vesiculated Golgi membranes) and inhibits vesicular protein transport between successive Golgi cisternae (Takizawa et al., 1993). While other intracellular organelles, intermediate filaments, and actin filaments are not affected, we have found that cytoplasmic microtubules are depolymerized by IQ treatment of NRK cells. We provide evidence that IQ breaks down Golgi membranes… CONTINUE READING

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