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icilin

Known as: AG-3-5 compound 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BackgroundOxaliplatin chemotherapy induced neuropathy is a dose related cumulative toxicity that manifests as tingling, numbness… Expand
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Highly Cited
2010
Highly Cited
2010
Somatosensory neurons detect environmental stimuli, converting external cues into neural activity that is relayed first to second… Expand
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Highly Cited
2008
Highly Cited
2008
The plant cannabinoids (phytocannabinoids), cannabidiol (CBD), and Δ9-tetrahydrocannabinol (THC) were previously shown to… Expand
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Highly Cited
2008
Highly Cited
2008
The activation of the TRPM8 channel, a member of the large class of TRP ion channels, has been reported to be involved in… Expand
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Highly Cited
2007
Highly Cited
2007
ThermoTRPs, a subset of the Transient Receptor Potential (TRP) family of cation channels, have been implicated in sensing… Expand
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Highly Cited
2007
Highly Cited
2007
Thermosensation is an essential sensory function that is subserved by a variety of transducer molecules, including those from the… Expand
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Highly Cited
2005
Highly Cited
2005
Members of the transient receptor potential (TRP) superfamily of ion channels have now been defined as molecular transducers… Expand
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Highly Cited
2004
Highly Cited
2004
TRPM8, a member of the transient receptor potential family of ion channels, depolarizes somatosensory neurons in response to cold… Expand
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Highly Cited
2004
Highly Cited
2004
TRPM8 is a nonselective cation channel activated by cold and the cooling compounds menthol and icilin (Peier et al., 2002). Here… Expand
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Highly Cited
2004
Highly Cited
2004
1. TRPM8 (CMR1) is a Ca(2+)-permeable channel, which can be activated by low temperatures, menthol, eucalyptol and icilin. It… Expand
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