icilin

Known as: AG-3-5 compound 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
05101519862018

Papers overview

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2010
2010
BACKGROUND Oxaliplatin chemotherapy induced neuropathy is a dose related cumulative toxicity that manifests as tingling, numbness… (More)
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Highly Cited
2010
Highly Cited
2010
Somatosensory neurons detect environmental stimuli, converting external cues into neural activity that is relayed first to second… (More)
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2009
2009
TRPM8 is a cation channel activated by cold temperatures and the chemical stimuli menthol and icilin. Both compounds use… (More)
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2008
2008
Icilin (AG-3-5) is a cold-inducing agent that activates the transient receptor potential channels TRPM8 and TRPA1. Both channels… (More)
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Highly Cited
2007
Highly Cited
2007
ThermoTRPs, a subset of the Transient Receptor Potential (TRP) family of cation channels, have been implicated in sensing… (More)
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Highly Cited
2007
Highly Cited
2007
Thermosensation is an essential sensory function that is subserved by a variety of transducer molecules, including those from the… (More)
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Highly Cited
2007
Highly Cited
2007
Members of the superfamily of transient receptor potential (TRP) channels are proposed to play important roles in sensory… (More)
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Highly Cited
2004
Highly Cited
2004
TRPM8, a member of the transient receptor potential family of ion channels, depolarizes somatosensory neurons in response to cold… (More)
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Highly Cited
2004
Highly Cited
2004
TRPM8 is a nonselective cation channel activated by cold and the cooling compounds menthol and icilin (Peier et al., 2002). Here… (More)
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Highly Cited
2004
Highly Cited
2004
1. TRPM8 (CMR1) is a Ca(2+)-permeable channel, which can be activated by low temperatures, menthol, eucalyptol and icilin. It… (More)
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