Skip to search formSkip to main contentSkip to account menu

icilin

Known as: AG-3-5 compound 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Pyrimidinones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Hydrogen peroxide preferentially activates capsaicin‐sensitive high threshold afferents via TRPA1 channels in the guinea pig bladder
There is increasing evidence suggesting that ROS play a major pathological role in bladder dysfunction induced by bladder… 
2017
2017
Synthesis and optimization of novel α-phenylglycinamides as selective TRPM8 antagonists.
2014
2014
Identification of a novel 2-pyridyl-benzensulfonamide derivative, RQ-00203078, as a selective and orally active TRPM8 antagonist.
2012
2012
Topical TRPM8 agonist (icilin) relieved vulva pruritus originating from lichen sclerosus et atrophicus.
Pruritus vulvae is caused by a variety of skin diseases, as well as by neuropathic/neurological, psychosomatic and psychiatric… 
Highly Cited
2007
Highly Cited
2007
TRPM8-independent Menthol-induced Ca2+ Release from Endoplasmic Reticulum and Golgi*
Menthol, a secondary alcohol produced by the peppermint herb, Mentha piperita, is widely used in the food and pharmaceutical… 
2007
2007
Transient Receptor Potential Channel TRPM8 Agonists Stimulate Calcium Influx and Neurotensin Secretion in Neuroendocrine Tumor Cells
TRPM8 is a member of the melastatin-type transient receptor potential ion channel family. Activation by cold or by agonists… 
2006
2006
Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine.
Highly Cited
2006
Highly Cited
2006
The Cold and Menthol Receptor TRPM8 Contains a Functionally Important Double Cysteine Motif*
We have investigated the glycosylation, disulfide bonding, and subunit structure of mouse TRPM8. To do this, amino-terminal c-myc… 
2005
2005
EGF suppresses hydrogen peroxide induced Ca2+ influx by inhibiting L-type channel activity in cultured human corneal endothelial cells.
2005
2005
Icilin Activates the δ-Subunit of the Human Epithelial Na+ Channel
The amiloride-sensitive epithelial Na+ channel (ENaC) regulates Na+ homeostasis in cells and across epithelia. Four homologous… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)