hypusine

Known as: (+)-hypusine, (R)-N6-(4-amino-2-hydroxybutyl)-L-lysine, N(6)-(4-amino-2-hydroxybutyl)-L-lysine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2018
0102019712018

Papers overview

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2010
2010
In both type 1 and type 2 diabetes, pancreatic islet dysfunction results in part from cytokine-mediated inflammation. The… (More)
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2009
Highly Cited
2009
Translation elongation factors facilitate protein synthesis by the ribosome. Previous studies identified two universally… (More)
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2009
2009
In searching for new targets for antimalarials we investigated the biosynthesis of hypusine present in eukaryotic initiation… (More)
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2006
2006
Eukaryotic initiation factor 5A (eIF5A) is the only protein in nature that contains hypusine, an unusual amino acid formed post… (More)
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1995
1995
Posttranslational modification of a specific lysine residue in eukaryotic initiation factor 5A (eIF-5A) is essential for cell… (More)
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1992
1992
The amino acid hypusine is formed by post-translational modification of a lysine residue in eukaryotes and archaebacteria but up… (More)
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Highly Cited
1991
Highly Cited
1991
Translation intitiation factor eIF-5A (previously named eIF-4D) is a highly conserved protein that promotes formation of the… (More)
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1987
1987
When mammalian cells are grown in medium containing [3H]spermidine, a single major tritiated protein identical to eukaryotic… (More)
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1983
1983
A single protein of Mr 17,000-19,000 and pI approximately equal to 5.1, found in all animal cells we have studied to date… (More)
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1981
1981
When normal human peripheral lymphocytes are treated with mitogen and grown in the presence of [3H]putrescine or [terminal… (More)
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