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hyperthermophile

National Institutes of Health

Papers overview

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2009
2009
Stability and solubility of proteins from extremophiles.
2008
2008
Di-myo-inositol phosphate and novel UDP-sugars accumulate in the extreme hyperthermophile Pyrolobus fumarii
The archaeon Pyrolobus fumarii, one of the most extreme members of hyperthermophiles known thus far, is able to grow at… 
2004
2004
Unusually slow denaturation and refolding processes of pyrrolidone carboxyl peptidase from a hyperthermophile are highly cooperative: real-time NMR studies.
The refolding rate of heat-denatured cysteine-free pyrrolidone carboxyl peptidase (PCP-0SH) from Pyrococcus furiosus has been… 
Highly Cited
2002
Highly Cited
2002
Stepwise adaptations of citrate synthase to survival at life's extremes. From psychrophile to hyperthermophile.
The crystal structure of citrate synthase from the thermophilic Archaeon Sulfolobus solfataricus (optimum growth temperature = 85… 
Highly Cited
2002
Highly Cited
2002
The unusually slow relaxation kinetics of the folding-unfolding of pyrrolidone carboxyl peptidase from a hyperthermophile, Pyrococcus furiosus.
In order to understand the thermodynamic and kinetic basis of the intrinsic stability of proteins from hyperthermophiles, the… 
2001
2001
X-ray crystalline structures of pyrrolidone carboxyl peptidase from a hyperthermophile, Pyrococcus furiosus, and its cys-free mutant.
In order to elucidate the mechanism of the thermostability of proteins from hyperthermophiles, X-ray crystalline structures of… 
2001
2001
Two kinds of archaeal chaperonin with different temperature dependency from a hyperthermophile.
Thermococcus kodakaraensis KOD1 produces two kinds of chaperonin subunits, CpkA and CpkB. To monitor the expression levels of… 
2000
2000
The process of amyloid-like fibril formation by methionine aminopeptidase from a hyperthermophile, Pyrococcus furiosus.
Amyloid is associated with serious diseases including Alzheimer's disease and senile-systemic amyloidosis due to misfolded… 
Highly Cited
1998
Highly Cited
1998
The unusually slow unfolding rate causes the high stability of pyrrolidone carboxyl peptidase from a hyperthermophile, Pyrococcus furiosus: equilibrium and kinetic studies of guanidine hydrochloride…
To elucidate the energetic features of the anomalously high-level stabilization of a hyperthermophile pyrrolidone carboxyl… 
Highly Cited
1996
Highly Cited
1996
A two-subunit type I DNA topoisomerase (reverse gyrase) from an extreme hyperthermophile.
A recently described reverse gyrase from the hyperthermophilic methanogen Methanopyrus kandleri is the only known example of a… 
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