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hydralazine pyruvic acid hydrazone

Known as: 2-(1-phthalazinylhydrazono)-propanoic acid 
National Institutes of Health

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Broader (1)

Hydralazine
analogs & derivatives

Papers overview

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1988
1988
In vitro kinetic studies of the reaction of hydralazine and its acetone hydrazone with pyruvic acid.
To understand the reaction between hydralazine (HP) or its acetone hydrazone (HAH), a metabolite of HP and pyruvic acid, a new… 
1985
1985
Synthesis, formulation, and clinical pharmacological evaluation of hydralazine pyruvic acid hydrazone in two healthy volunteers.
Hydralazine pyruvic acid hydrazone [2-(phthalazin-1-yl hydrazono)propionic acid; 1] is a major plasma metabolite of hydralazine… 
1984
1984
Effect of food on blood hydralazine levels and response in hypertension
A study with a nonspecific hydralazine assay reported that food increased hydralazine concentrations in plasma. We used a… 
1983
1983
Effect of intravenous dose on hydralazine kinetics after administration
Six male hypertensive patients, three rapid and three slow acetylators, each received four different intravenous hydralazine… 
1981
1981
Determination of hydralazine pyruvic acid hydrazone and its correlation with "apparent" hydralazine.
Highly Cited
1980
Highly Cited
1980
Kinetics of hydralazine and its main metabolites in slow and fast acetylators
Kinetics of hydralazine (HP) and its metabolites, hydralazine pyruvic acid hydrazone (HPPAH) and 3‐methyl‐s‐triazolo[3,4‐a… 
1980
1980
Quantitative analysis of hydralazine pyruvic acid hydrazone, the major plasma metabolite of hydralazine.
1980
1980
Tachycardia associated with hydralazine pyruvic acid hydrazone the major plasma metabolite of hydralazine
1979
1979
Pharmacokinetics of hydralazine, apparent hydralazine and hydralazine pyruvic acid hydrazone in humans.
Hydralazine is an antihypertensive vasodilator agent. Lack of specific assay techniques for its measurement have delayed… 
1979
1979
High-pressure liquid chromatographic assay for hydralazine in human plasma.
A specific high-performance liquid chromatographic assay for hydralazine in human plasma was developed. Plasma hydralazine is… 
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