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Hydralazine

Known as: Hydralazinum, Hydrallazin, Phthalazin-1-ylhydrazine 
A phthalazine derivative with antihypertensive effects. Hydralazine exerts its vasodilatory effects through modification of the contractile state of… 
National Institutes of Health

Related topics

Related topics

39 relations
1 ML Hydralazine Hydrochloride 20 MG/ML InjectionArterial Vasodilation [PE]Arteriolar Vasodilation [PE]Congestive heart failure

Broader (5)

Antihypertensive AgentsHydrazineHydrazinesSympatholytics

Narrower (9)

ApresolineBidilHyparezbisvanillyl-hydralazone

Papers overview

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Highly Cited
1985
Highly Cited
1985
Effects of Long‐term Antihypertensive Treatment on Kidney Function in Diabetic Nephropathy
The purpose of our prospective study was to evaluate the long-term effect of aggressive antihypertensive treatment on glomerular… 
Review
1984
Review
1984
Direct vasodilators with unknown modes of action: the nitro-compounds and hydralazine.
Several aspects of the mode of action of direct vasodilators are discussed. Nitro-compounds probably act via an intracellular… 
Highly Cited
1982
Highly Cited
1982
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats.
Prolonged treatment of spontaneously hypertensive (SHR) rats with either methyldopa or clonidine significantly and similarly… 
1982
1982
The effects of oral hydralazine on right ventricular end-diastolic pressure in patients with right ventricular failure.
Hydralazine reduces pulmonary vascular resistance in patients with primary and secondary pulmonary hypertension, but the effects… 
Highly Cited
1981
Highly Cited
1981
Prazosin and hydralazine in congestive heart failure. Regional hemodynamic effects in relation to dose.
Central hemodynamic variables and regional blood flow and vascular resistances were ascertained in patients with severe… 
Highly Cited
1980
Highly Cited
1980
Renal Effects of Nitroprusside and Hydralazine in Patients with Congestive Heart Failure
SUMMARYThe acute effects of nitroprusside infusion and intravenous hydralazine on renal hemodynamics and function were evaluated… 
1980
1980
Effect of Hydralazine on Renal Failure in Patients with Congestive Heart Failure
SUMMARYHydralazine is known to improve cardiac function in patients with congestive heart failure (CHF), but its effects on renal… 
1954
1954
Studies on the control of hypertension by hyphex. III. Pharmacological and chemical observations on 1-hydrazinophthalazine.
1952
1952
Evaluation of l-hydrazinophthalazine (apresoline) in treatment of hypertensive disease.
Highly Cited
1951
Highly Cited
1951
Some pharmacodynamic effects of 1-hydrazinophthalazine (C-5968) with particular reference to renal function and cardiovascular response.