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homocysteine
Known as:
2-Amino-4-Mercapto-Butyric acid
, Butanoic Acid, 2-Amino-4-Mercapto-
, 2-Amino-4-Sulfanylbutanoic Acid
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An amino acid derivative and homolog of cysteine containing an additional methylene bridge. Homocysteine is a product of methionine metabolism and…
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National Institutes of Health
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Related topics
Related topics
41 relations
Narrower (17)
5-(2-aminoethyl)homocysteine
N-homocysteine thiolactonyl retinamide
N-homocysteine thiolactonyl retinamido cobalamin
N-homocysteinylated albumin
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5-Methyltetrahydrofolate homocysteine methyltransferase:CCnc:Pt:Ser:Qn
Adenosyl homocysteine hydrolase:CCnt:Pt:RBC:Qn
Homocysteine cysteine disulfide/Creatinine:Ratio:Pt:Urine:Qn
Homocysteine cysteine disulfide/Creatinine:SRto:Pt:Urine:Qn
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Broader (1)
Amino Acids, Sulfur
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial
J. Durga
,
M. Boxtel
,
+4 authors
P. Verhoef
The Lancet
2007
Corpus ID: 20395823
Review
2006
Review
2006
The Hordaland Homocysteine Study: a community-based study of homocysteine, its determinants, and associations with disease.
H. Refsum
,
H. Refsum
,
+9 authors
S. Vollset
Journal of NutriLife
2006
Corpus ID: 13677290
The Hordaland Homocysteine Study (HHS) is a population-based study of more than 18,000 men and women in the county of Hordaland…
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Highly Cited
2006
Highly Cited
2006
A controlled trial of homocysteine lowering and cognitive performance.
Jennifer A. McMahon
,
T. Green
,
C. Skeaff
,
R. Knight
,
J. Mann
,
Sheila M. Williams
New England Journal of Medicine
2006
Corpus ID: 7583033
BACKGROUND The results of observational studies suggest that plasma homocysteine concentrations are inversely related to…
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Highly Cited
2005
Highly Cited
2005
Detection of Homocysteine and Cysteine
Weihua Wang
,
O. Rusin
,
+10 authors
R. Strongin
2005
Corpus ID: 45506395
At elevated levels, homocysteine (Hcy, 1) is a risk factor for cardiovascular diseases, Alzheimer's disease, neural tube defects…
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Highly Cited
2005
Highly Cited
2005
Mechanisms of homocysteine-induced oxidative stress.
N. Tyagi
,
Kara C. Sedoris
,
M. Steed
,
A. Ovechkin
,
K. Moshal
,
S. Tyagi
American Journal of Physiology. Heart and…
2005
Corpus ID: 13153412
Hyperhomocysteinemia decreases vascular reactivity and is associated with cardiovascular morbidity and mortality. However…
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Highly Cited
2005
Highly Cited
2005
Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials.
R. Clarke
,
C. Frost
,
+41 authors
N. Wald
American Journal of Clinical Nutrition
2005
Corpus ID: 4437155
BACKGROUND Dietary supplementation with B vitamins that lower blood homocysteine concentrations is expected to reduce…
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Review
2003
Review
2003
Malnutrition-inflammation complex syndrome in dialysis patients: causes and consequences.
Kamyar Kalantar-Zadeh
,
Kamyar Kalantar-Zadeh
,
+5 authors
J. Kopple
American Journal of Kidney Diseases
2003
Corpus ID: 26457475
Highly Cited
2002
Highly Cited
2002
Folic Acid Deficiency and Homocysteine Impair DNA Repair in Hippocampal Neurons and Sensitize Them to Amyloid Toxicity in Experimental Models of Alzheimer's Disease
I. Kruman
,
T. Kumaravel
,
+7 authors
M. Mattson
Journal of Neuroscience
2002
Corpus ID: 635131
Recent epidemiological and clinical data suggest that persons with low folic acid levels and elevated homocysteine levels are at…
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Review
1999
Review
1999
Homocysteine and Alzheimer's disease.
Joshua W. Miller
Nutrition reviews
1999
Corpus ID: 8275103
In a recent case-control study of 164 patients with clinically diagnosed Alzheimer's disease (AD), including 76 patients with the…
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Review
1998
Review
1998
Homocysteine and vitamins in cardiovascular disease.
D. Jacobsen
Clinical Chemistry
1998
Corpus ID: 1500927
On the basis of recent retrospective and prospective studies, it is now widely accepted that increased total plasma homocysteine…
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