histone demethylation

The modification of histones by removal of methyl groups. [GOC:ai]
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2017
05101520042017

Papers overview

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Highly Cited
2014
Highly Cited
2014
Pediatric brainstem gliomas often harbor oncogenic K27M mutation of histone H3.3. Here we show that GSKJ4 pharmacologic… (More)
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2013
2013
Epigenetic modifications of chromatin represent a fundamental mechanism by which eukaryotic cells adapt their transcriptional… (More)
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2013
2013
Aberrant gluconeogenic gene expression is associated with diabetes, glycogen storage disease, and liver cancer. However, little… (More)
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Highly Cited
2012
Highly Cited
2012
Recurrent mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 have been identified in gliomas, acute myeloid leukaemias (AML… (More)
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2012
2012
The Jumonji C domain-containing histone demethylases (JmjC-HDMs) are α-ketoglutarate (αKG)-dependent, O(2)-activating, non-heme… (More)
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2011
2011
Gene expression is controlled by epigenetic mechanisms such as histone acetylation and methylation, and recent studies have… (More)
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2011
2011
Abnormal activities of histone lysine demethylases (KDMs) and lysine deacetylases (HDACs) are associated with aberrant gene… (More)
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2010
2010
Activation of transcription from a silenced state is crucial to achieve specific gene expression in many biological contexts… (More)
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2010
2010
Post-translational modifications on histones are an important mechanism for the regulation of gene expression and are involved in… (More)
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Highly Cited
2004
Highly Cited
2004
Posttranslational modifications of histone N-terminal tails impact chromatin structure and gene transcription. While the extent… (More)
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