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histone demethylation

The modification of histones by removal of methyl groups. [GOC:ai]
National Institutes of Health

Papers overview

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2016
2016
OBJECTIVE To investigate whether epigenetic changes can modulate monocytes to produce tissue inhibitor of metalloproteinases 1… Expand
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2015
2015
Polycomb group proteins are epigenetic transcriptional repressors that function through recognition and modification of histone… Expand
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2013
2013
Aberrant gluconeogenic gene expression is associated with diabetes, glycogen storage disease, and liver cancer. However, little… Expand
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Highly Cited
2012
Highly Cited
2012
Recurrent mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 have been identified in gliomas, acute myeloid leukaemias (AML… Expand
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2012
2012
The Jumonji C domain-containing histone demethylases (JmjC-HDMs) are α-ketoglutarate (αKG)-dependent, O(2)-activating, non-heme… Expand
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2012
2012
Objective This study investigated the epigenetic role of PRL-3, a key metastasis gene in colorectal cancer (CRC), as a regulator… Expand
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Highly Cited
2011
Highly Cited
2011
Abnormal activities of histone lysine demethylases (KDMs) and lysine deacetylases (HDACs) are associated with aberrant gene… Expand
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Review
2007
Review
2007
The recent discovery that histone demethylation can be catalyzed by the flavin-dependent amine oxidase LSD1 has ushered in a new… Expand
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Highly Cited
2006
Highly Cited
2006
Histone methylation has important roles in regulating gene expression and forms part of the epigenetic memory system that… Expand
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Highly Cited
2004
Highly Cited
2004
Posttranslational modifications of histone N-terminal tails impact chromatin structure and gene transcription. While the extent… Expand
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