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Regulation of LSD1 histone demethylase activity by its associated factors.
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Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2.
TLDR
In livers from GLD-2-null mice, the steady-state level of the mature form of miR-122 was specifically lower than in heterozygous mice, whereas no reduction of pre-miR- 122 was observed, demonstrating that 3'-terminal adenylation by GLd-2 is required for the selective stabilization of mi R-122 in the liver.
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Possible Function of the ADAM1a/ADAM2 Fertilin Complex in the Appearance of ADAM3 on the Sperm Surface*
TLDR
It is suggested that ADAM1a/ADAM2 fertilin may be implicated in the selective transport of specific sperm proteins including ADAM3 from the endoplasmic reticulum of testicular germ cells onto the cell surface and participate in sperm migration into the oviduct, the dispersal of cumulus cells, and sperm binding to the zona pellucida.
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Mouse Sperm Lacking Cell Surface Hyaluronidase PH-20 Can Pass through the Layer of Cumulus Cells and Fertilize the Egg*
TLDR
Evidence thatPH-20 is not essential for fertilization, at least in the mouse is provided, suggesting that the other hyaluronidase(s) may play an important role in sperm penetration through the cumulus cell layer and/or the egg zona pellucida, possibly in cooperation with PH-20, although the importance of sperm motility cannot be neglected.
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Sperm from mice carrying a targeted mutation of the acrosin gene can penetrate the oocyte zona pellucida and effect fertilization.
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An acrosomal protein, sp32, in mammalian sperm is a binding protein specific for two proacrosins and an acrosin intermediate.
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Identification, cDNA Cloning, and Gene Expression of Soluble Starch Synthase in Rice (Oryza sativa L.) Immature Seeds
TLDR
The results suggest that soluble and granule-bound starch synthases play distinct roles in starch biosynthesis of plant.
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Real‐time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein
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A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory
TLDR
The observations indicate that Oct‐1‐binding followed by CpG demethylation are key events in the epigenetic regulation of IL2 expression and may act as a memory of the regulatory event.
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Identification of a hyaluronidase, Hyal5, involved in penetration of mouse sperm through cumulus mass.
TLDR
Results suggest that in the mouse, Hyal5 may function principally as a "cumulus matrix depolymerase" in the sperm penetration through the cumulus mass and in the local hyaluronan hydrolysis near or on the surface of the egg zona pellucida to enable the proximal region of sperm tail to move freely.
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