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hirugen

Known as: hirudin (53-64), O-sulfotyrosine(63)-, hirudin dodecapeptide, 63-O-sulfo-Tyr-hirudin (53-64) 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

BG 8865

Broader (2)

HirudinsPeptide Fragments

Papers overview

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2016
2016
Fibrinogen &ggr;-Chain Peptide–Coated Adenosine 5' Diphosphate–Encapsulated Liposomes Rescue Mice From Lethal Blast Lung Injury via Adenosine Signaling*
Objectives: Fibrinogen &ggr;-chain (dodecapeptide HHLGGAKQAGDV)-coated adenosine 5′-diphosphate–encapsulated liposomes can… 
2014
2014
Functional analysis of kisspeptin peptides in adult immature chub mackerel (Scomber japonicus) using an intracerebroventricular administration method
2011
2011
Ultrastructural analysis of thrombin-induced interaction between human platelets and liposomes carrying fibrinogen γ-chain dodecapeptide as a synthetic platelet substitute.
2009
2009
The effects of exosite occupancy on the substrate specificity of thrombin.
1999
1999
The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a…
Substitution of the native variable region-1 (VR1/37-loop) of thrombin by the corresponding VR1 of tissue-type plasminogen… 
1995
1995
Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution.
Crystals of human alpha-thrombin complexed with hirugen and the alpha-keto acid thrombin inhibitor APPA (p-amidinophenylpyruvate… 
Highly Cited
1992
Highly Cited
1992
Regulation of the urokinase-type plasminogen activator receptor on vascular smooth muscle cells is under the control of thrombin and other mitogens.
The urokinase-type plasminogen activator receptor (u-PAR) was demonstrated on cultured smooth muscle cells (SMCs) of bovine aorta… 
1992
1992
Inhibition of the amplification reactions of blood coagulation by site-specific inhibitors of alpha-thrombin.
Hirudin and hirulog-1 [D-Phe-Pro-Arg-Pro-[Gly]4-desulphohirudin-(54-65)] abrogate the enzyme activities of alpha-thrombin by… 
1992
1992
Thrombin inhibition enhances tissue-type plasminogen activator-induced thrombolysis and delays reocclusion.
The objectives of this study were to test the hypotheses that thrombin inhibitors 1) enhance tissue-type plasminogen activator (t… 
1991
1991
Proteolytic formation of either of the two prothrombin activation intermediates results in formation of a hirugen-binding site.
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