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hepatocyte proliferation

The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of… 
National Institutes of Health

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regulation of hepatocyte proliferation

Papers overview

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Highly Cited
2012
Highly Cited
2012
Suppression of Hepatocyte Proliferation by Hepatocyte Nuclear Factor 4α in Adult Mice*
Background: HNF4α is a key factor regulating hepatocyte differentiation and liver-specific functions. Results: Acute disruption… 
Highly Cited
2009
Highly Cited
2009
FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation
FGF19 and FGF21, unique members of the fibroblast growth factor (FGF) family, are hormones that regulate glucose, lipid, and… 
Highly Cited
2007
Highly Cited
2007
p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway
The mitogen-activated protein kinase (MAPK) p38α controls inflammatory responses and cell proliferation. Using mice carrying… 
Highly Cited
2007
Highly Cited
2007
Liver‐specific loss of β‐catenin results in delayed hepatocyte proliferation after partial hepatectomy
Recent studies have suggested that β‐catenin is involved in the regulation of hepatocyte proliferation in multiple contexts… 
Highly Cited
2003
Highly Cited
2003
Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis.
Highly Cited
2002
Highly Cited
2002
Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c‐jun in the liver
Mice lacking the AP‐1 transcription factor c‐jun die at mid‐gestation showing heart defects and impaired hepatogenesis. To… 
Highly Cited
1998
Highly Cited
1998
Interleukin‐10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice
The role of the anti‐inflammatory cytokine interleukin‐10 (IL‐10) was investigated in the mouse model of liver injury induced by… 
Highly Cited
1997
Highly Cited
1997
CCAAT/enhancer binding protein alpha regulates p21 protein and hepatocyte proliferation in newborn mice
CCAAT/enhancer binding protein alpha (C/EBP alpha) is expressed at high levels in quiescent hepatocytes and in differentiated… 
Highly Cited
1995
Highly Cited
1995
Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation.
Expression of the group of cytokines known as transforming growth factor-beta (TGF-beta 1, -beta 2 and -beta 3) is increased… 
Highly Cited
1991
Highly Cited
1991
Expression of hepatocyte growth factor mRNA in regenerating rat liver after partial hepatectomy.
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