hepatitis B virus X protein

Known as: hepatitis B virus X antigen, viral X protein, Hepatitis B virus, HBxAg, HBV 
Hepatitis B virus X protein; a hepatitis B viral product relevant to hepatocarcinogenesis.
National Institutes of Health

Related topics

Related topics

3 relations
Genes, ViralVirus

Broader (1)

Trans-Activators

Papers overview

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Highly Cited
2013
Highly Cited
2013
Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.
MicroRNAs (miRNAs) have been shown to be dysregulated in virus-related cancers; however, miRNA regulation of virus-related cancer… (More)
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Highly Cited
2009
Highly Cited
2009
Liver X receptor mediates hepatitis B virus X protein-induced lipogenesis in hepatitis B virus-associated hepatocellular carcinoma.
UNLABELLED Although hepatitis B virus X protein (HBx) has been implicated in abnormal lipid metabolism in hepatitis B virus (HBV… (More)
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Highly Cited
2005
Highly Cited
2005
Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1
E-cadherin is a key cell adhesion molecule implicated as a tumor suppressor, which is frequently altered in hepatocellular… (More)
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Highly Cited
2001
Highly Cited
2001
Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress.
The hepatitis B virus X protein (HBx) plays essential roles in viral replication and the generation of hepatocellular carcinoma… (More)
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Highly Cited
2001
Highly Cited
2001
Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues.
The hepatitis B virus (HBV) X protein (HBx) is a transcriptional transactivator that has been implicated in the development of… (More)
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Highly Cited
1999
Highly Cited
1999
Hepatitis B virus X protein inhibits nucleotide excision repair.
Human hepatitis B virus (HBV) is a major risk factor of human hepatocellular carcinoma. Both in vivo and in vitro studies have… (More)
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Highly Cited
1999
Highly Cited
1999
Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex.
The hepatitis B virus X protein (HBX) is essential for the establishment of HBV infection in vivo and exerts a pleiotropic effect… (More)
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Highly Cited
1998
Highly Cited
1998
Hepatitis B virus X protein interferes with cellular DNA repair.
The hepatitis B virus X protein (HBx) is a broadly acting transactivator implicated in the development of liver cancer. Recently… (More)
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Highly Cited
1998
Highly Cited
1998
Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas.
Transactivation of cellular genes and functional inactivation of p53 by the hepatitis B virus (HBV) X gene-encoded protein (HBx… (More)
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Highly Cited
1997
Highly Cited
1997
Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis.
We have reported previously that the hepatitis B virus oncoprotein, HBx, can bind to the C terminus of p53 and inhibit several… (More)
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