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hepatitis B virus X protein

Known as: hepatitis B virus X antigen, viral X protein, Hepatitis B virus, HBxAg, HBV 
Hepatitis B virus X protein; a hepatitis B viral product relevant to hepatocarcinogenesis.
National Institutes of Health

Related topics

Related topics

3 relations
Genes, ViralVirus

Broader (1)

Trans-Activators

Papers overview

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2012
2012
Altered Binding Site Selection of p53 Transcription Cassettes by Hepatitis B Virus X Protein
ABSTRACT The key cellular regulator p53 is a common target of viral oncoproteins. However, the mechanism by which p53… 
Highly Cited
2004
Highly Cited
2004
Sustained Activation of p38 Mitogen-Activated Protein Kinase and c-Jun N-Terminal Kinase Pathways by Hepatitis B Virus X Protein Mediates Apoptosis via Induction of Fas/FasL and Tumor Necrosis Factor…
ABSTRACT Activation of the cellular stress pathways (c-Jun N-terminal kinase [JNK] and p38 mitogen-activated protein [MAP] kinase… 
Highly Cited
2003
Highly Cited
2003
Caspase-dependent Alterations of Ca2+ Signaling in the Induction of Apoptosis by Hepatitis B Virus X Protein*
The hepatitis B virus X protein (HBx) is a multifunctional protein, acting on different targets (e.g. transcription factors… 
2002
2002
SAGE transcript profiles of normal primary human hepatocytes expressing oncogenic hepatitis B virus X protein
Hepatitis B virus (HBV) is a major risk factor for hepatocellular carcinoma (HCC). HBV encodes an oncogenic HBx gene that… 
Highly Cited
2001
Highly Cited
2001
Distinctive gene expression profiles associated with Hepatitis B virus x protein
Hepatitis B virus (HBV) is a major risk factor for the development of hepatocellular carcinoma (HCC). HBV encodes the potentially… 
Highly Cited
2001
Highly Cited
2001
The Hepatitis B Virus X Protein Induces HIV-1 Replication and Transcription in Synergy with T-cell Activation Signals
Co-infection with hepatitis B virus (HBV) and human immunodeficiency virus type-1 (HIV-1) is relatively common. However, the… 
Highly Cited
1998
Highly Cited
1998
Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome
The hepatitis B virus X protein plays an important role in the regulation of viral genome expression and has also been implicated… 
Highly Cited
1998
Highly Cited
1998
Regulation of RNA Polymerase I-Dependent Promoters by the Hepatitis B Virus X Protein via Activated Ras and TATA-Binding Protein
ABSTRACT The hepatitis B virus (HBV) X protein is essential for viral infectivity, and evidence indicates that it is a strong… 
1998
1998
Properties of tumour suppressor p53 in murine hepatocyte lines transformed by hepatitis B virus X protein.
Persistent infection by hepatitis B virus (HBV) correlates with the prevalence of hepatocellular carcinoma. It has recently been… 
Highly Cited
1990
Highly Cited
1990
Hepatitis B virus X protein transactivates the long terminal repeats of human immunodeficiency virus types 1 and 2
The X gene product of the hepatitis B virus (HBV) has been expressed transiently in HepG2 cells, and the 17-kilodalton protein… 
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