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helicase activity

Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix. [GOC:mah, ISBN:0198506732]
National Institutes of Health

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2 relations
DNA HelicasesDNA2 gene

Papers overview

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2010
2010
Disease Variants of the Human Mitochondrial DNA Helicase Encoded by C10orf2 Differentially Alter Protein Stability, Nucleotide Hydrolysis, and Helicase Activity*♦
Missense mutations in the human C10orf2 gene, encoding the mitochondrial DNA (mtDNA) helicase, co-segregate with mitochondrial… 
Highly Cited
2008
Highly Cited
2008
Ring expanded nucleoside analogues inhibit RNA helicase and intracellular human immunodeficiency virus type 1 replication.
A series of ring expanded nucleoside (REN) analogues were synthesized and screened for inhibition of cellular RNA helicase… 
Highly Cited
2006
Highly Cited
2006
Phosphorylation of MCM4 at Sites Inactivating DNA Helicase Activity of the MCM4-MCM6-MCM7 Complex during Epstein-Barr Virus Productive Replication
ABSTRACT Induction of Epstein-Barr virus (EBV) lytic replication blocks chromosomal DNA replication notwithstanding an S-phase… 
Highly Cited
2003
Highly Cited
2003
The Werner Syndrome Protein Stimulates DNA Polymerase β Strand Displacement Synthesis via Its Helicase Activity*
Werner syndrome is a hereditary premature aging disorder characterized by genomic instability. Genetic analysis and protein… 
Highly Cited
2000
Highly Cited
2000
Elevation of sister chromatid exchange in Saccharomyces cerevisiae sgs1 disruptants and the relevance of the disruptants as a system to evaluate mutations in Bloom's syndrome gene.
Highly Cited
1995
Highly Cited
1995
RNA helicase activity of the plum pox potyvirus CI protein expressed in Escherichia coli. Mapping of an RNA binding domain.
The plum pox potyvirus (PPV) cylindrical inclusion (CI) protein fused to the maltose binding protein (MBP) has been synthesized… 
Highly Cited
1993
Highly Cited
1993
The nucleotide binding site of the helicase/primase of bacteriophage T7. Interaction of mutant and wild-type proteins.
1989
1989
The Escherichia coli primosome can translocate actively in either direction along a DNA strand.
1988
1988
Further characterization of DNA helicase activity of mouse DNA-dependent adenosinetriphosphatase B (DNA helicase B).
The DNA helicase activity of DNA-dependent ATPase B purified from mouse FM3A cells [Seki, M., Enomoto, T., Hanaoka, F., & Yamada… 
1986
1986
Interactions of the DNA polymerase and gene 4 protein of bacteriophage T7. Protein-protein and protein-DNA interactions involved in RNA-primed DNA synthesis.
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