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hedamycin

National Institutes of Health

Papers overview

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2011
2011
Bacterial aromatic polyketides that include many antibiotic and antitumor therapeutics are biosynthesized by the type II… 
Highly Cited
2005
Highly Cited
2005
Expression of the antiapoptotic protein survivin is associated with cancer cell viability and drug resistance. Thus, control of… 
2005
2005
Genotoxic treatments, such as UV light, camptothecin, and adozelesin, stall DNA replication and subsequently generate DNA strand… 
2001
1996
1996
2D NMR spectroscopic methods have been used to determine the structure of the adduct formed between the antitumor antibiotic… 
Highly Cited
1994
Highly Cited
1994
TBP (TATA box binding protein), a general transcription factor required for proper initiation of gene expression by RNA… 
1985
1985
The cytotoxicities of hedamycin and photohedamycin A as well as of kidamycin and isokidamycin were determined using HeLa cell… 
1982
1982
  • G. Bennett
  • Nucleic acids research
  • 1982
  • Corpus ID: 6093693
Hedamycin forms a stable complex with DNA and introduces alkali labile linkages in the DNA. These labile linkages are located at…