Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

hammerhead ribozyme

Known as: ribozyme, hammerhead 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Systems for conditional gene expression are powerful tools in basic research as well as in biotechnology. For future applications… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Review
2013
Review
2013
The hammerhead ribozyme has long been considered a prototype for understanding RNA catalysis, but discrepancies between the… Expand
Highly Cited
2003
Highly Cited
2003
The hammerhead ribozyme is one of the best-studied small RNA enzymes, yet is mechanistically still poorly understood. We measured… Expand
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
2001
2001
PURPOSE To develop a hammerhead ribozyme-based gene therapy for a porcine model of autosomal dominant retinitis pigmentosa (ADRP… Expand
1999
1999
An improved method is presented for the preparation of milligram quantities of homogenous-length RNAs suitable for nuclear… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 5
Highly Cited
1995
Highly Cited
1995
Several 2'-modified ribonucleoside phosphoramidites have been prepared for structure-activity studies of the hammerhead ribozyme… Expand
Highly Cited
1994
Highly Cited
1994
For the understanding of the catalytic function of the RNA hammerhead ribozyme, a three-dimensional model is essential but… Expand
Highly Cited
1994
Highly Cited
1994
A major problem in cytostatic treatment of many tumours is the development of multidrug resistance (MDR4). This is most often… Expand
  • figure 4
1994
1994
Hammerhead ribozyme-inhibitor complexes consisting of an RNA "enzyme" strand and a DNA "inhibitor" strand have been crystallized… Expand
Highly Cited
1993
Highly Cited
1993
The three guanosines of the central core of a hammerhead ribozyme were replaced by 2-aminopurine ribonucleoside, xanthosine… Expand