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hammerhead ribozyme

Known as: ribozyme, hammerhead 
 
National Institutes of Health

Papers overview

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2015
2015
Systems for conditional gene expression are powerful tools in basic research as well as in biotechnology. For future applications… Expand
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Review
2013
Review
2013
The hammerhead ribozyme has long been considered a prototype for understanding RNA catalysis, but discrepancies between the… Expand
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2010
2010
Computational studies of the mutational effects at the C3, G8, and G5 positions of the hammerhead ribozyme (HHR) are reported… Expand
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Review
2004
Review
2004
The limited efficacy of current therapeutic approaches for a number of socially relevant human diseases such as cancer and… Expand
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2003
2003
The hammerhead ribozyme is one of the best-studied small RNA enzymes, yet is mechanistically still poorly understood. We measured… Expand
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2001
2001
PURPOSE To develop a hammerhead ribozyme-based gene therapy for a porcine model of autosomal dominant retinitis pigmentosa (ADRP… Expand
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Highly Cited
1994
Highly Cited
1994
For the understanding of the catalytic function of the RNA hammerhead ribozyme, a three-dimensional model is essential but… Expand
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1994
1994
A major problem in cytostatic treatment of many tumours is the development of multidrug resistance (MDR4). This is most often… Expand
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1993
1993
Abstract Hammerhead ribozyme-inhibitor complexes consisting of an RNA "enzyme" strand and a DNA "inhibitor" strand have been… Expand
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1993
1993
The three guanosines of the central core of a hammerhead ribozyme were replaced by 2-aminopurine ribonucleoside, xanthosine… Expand
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