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haloalkane dehalogenase

Known as: 1-chlorohexane halidohydrolase 
National Institutes of Health

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2 relations

Broader (1)

Hydrolase
haloalkane dehalogenase activity

Papers overview

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Highly Cited
2007
Highly Cited
2007
Phylogenetic analysis of haloalkane dehalogenases
Haloalkane dehalogenases (HLDs) are enzymes that catalyze the cleavage of carbon–halogen bonds by a hydrolytic mechanism… 
Highly Cited
2005
Highly Cited
2005
Degradation of β-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26
ABSTRACT β-Hexachlorocyclohexane (β-HCH) is the most recalcitrant among the α-, β-, γ-, and δ-isomers of HCH and causes serious… 
Highly Cited
2002
Highly Cited
2002
Biodegradation of 1,2,3-Trichloropropane through Directed Evolution and Heterologous Expression of a Haloalkane Dehalogenase Gene
ABSTRACT Using a combined strategy of random mutagenesis of haloalkane dehalogenase and genetic engineering of a chloropropanol… 
Highly Cited
2000
Highly Cited
2000
Crystal structure of the haloalkane dehalogenase from Sphingomonas paucimobilis UT26.
The haloalkane dehalogenase from Sphingomonas paucimobilis UT26 (LinB) is the enzyme involved in the degradation of the important… 
Highly Cited
1997
Highly Cited
1997
Purification and characterization of a haloalkane dehalogenase of a new substrate class from a gamma-hexachlorocyclohexane-degrading bacterium, Sphingomonas paucimobilis UT26
The linB gene product (LinB), 1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase, which is involved in the degradation of… 
Highly Cited
1994
Highly Cited
1994
The role of spontaneous cap domain mutations in haloalkane dehalogenase specificity and evolution.
The first step in the utilization of the xenobiotic chlorinated hydrocarbon 1,2-dichloroethane by Xanthobacter autotrophicus is… 
Highly Cited
1994
Highly Cited
1994
Site-directed mutagenesis and oxygen isotope incorporation studies of the nucleophilic aspartate of haloalkane dehalogenase.
Haloalkane dehalogenase catalyzes the hydrolytic cleavage of carbon-halogen bonds in a broad range of halogenated aliphatic… 
Highly Cited
1993
Highly Cited
1993
Refined X-ray structures of haloalkane dehalogenase at pH 6.2 and pH 8.2 and implications for the reaction mechanism.
The crystal structure of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10 has been refined at 1.9 A resolution at two… 
Highly Cited
1987
Highly Cited
1987
Purification and properties of haloalkane dehalogenase from Corynebacterium sp. strain m15-3
A haloalkane dehalogenase was purified to electrophoretic homogeneity from cell extracts of a 1-chlorobutane-utilizing strain… 
Highly Cited
1985
Highly Cited
1985
Purification and characterization of hydrolytic haloalkane dehalogenase from Xanthobacter autotrophicus GJ10
A new enzyme, haloalkane dehalogenase, was isolated from the 1,2-dichloroethane-utilizing bacterium Xanthobacter autotrophicus… 
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