Skip to search formSkip to main contentSkip to account menu

guanoxabenz

Known as: 1-(2,6-dichlorobenzylideneamino)-3-hydroxyguanidine 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Guanabenz
analogs & derivatives

Narrower (1)

guanoxabenz hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Identification of an N-hydroxyguanidine reducing activity of xanthine oxidase.
A guanoxabenz [1-(2,6-dichlorobenzylideneamino)-3-hydroxyguanidine; an N-hydroxyguanidine] reducing enzymatic activity of rat… 
1996
1996
Microsomal catalyzed N-hydroxylation of guanabenz and reduction of the N-hydroxylated metabolite: characterization of the two reactions and genotoxic potential of guanoxabenz.
The N-reduction of the centrally acting alpha 2-adrenoreceptor agonist guanoxabenz (Benzérial), an N-hydroxyamidinohydrazone, to… 
1996
1996
α2-autoreceptors and α2-heteroreceptors modulating tyrosine and tryptophan hydroxylase activity in the rat brain in vivo: an investigation into the α2-adrenoceptor subtypes
The subtype determination of auto- and hetero-α2-adrenoceptors modulating the synthesis of noradrenaline (NA) and serotonin (5-HT… 
1994
1994
Alpha 2-adrenoceptor subtypes identified by [3H]RX821002 binding in the human brain: the agonist guanoxabenz does not discriminate different forms of the predominant alpha 2A subtype.
Competition [3H]RX821002 ([3H]2-methoxyidazoxan) binding experiments with alpha 2-adrenoceptor subtype-specific antagonists--BRL… 
1993
1993
Further evidence for the existence of two forms of alpha 2B-adrenoceptors in rat.
Analysis of saturation isotherms of the novel alpha 2-adrenoceptor antagonist radioligand [3H]-MK 912 revealed that the ligand… 
1985
1985
Effects of delta-aminolaevulinic acid on contractile activity in the isolated small intestine of the rabbit Role of adrenergic receptors
1984
1984
2‐Alkyl analogues of idazoxan (RX 781094) with enhanced antagonist potency and selectivity at central α2‐adrenoceptors in the rat
1 Four 2‐alkyl (methyl, ethyl, n‐propyl and isopropenyl) analogues of idazoxan (RX 781094) have been synthesized and assessed in… 
Highly Cited
1983
Highly Cited
1983
Neuropharmacological studies in rodents on the action of RX 781094, a new selective α2-adrenoceptor antagonist
1983
1983
Evidence for pharmacological similarity between α2,‐adrenoceptors in the vas deferens and central nervous system of the rat
1 Seven α2‐adrenoceptor antagonists with diverse chemical structures have been examined for their effects at α2‐adrenoceptors in… 
1981
1981
Studies on the pre- and postjunctional activities of alpha-adrenoreceptor agonists and their cardiovascular effects in the anaesthetized rat.
1 The selectivity of a number of agonists for peripheral alpha 1- and alpha 2- adrenoreceptors was determined and related to… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)