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Guanabenz

Known as: 2,6-Dichlorobenzylideneaminoguanidine, Guanabenzum, Guanabenzo 
An alpha-2 selective adrenergic agonist used as an antihypertensive agent.
National Institutes of Health

Papers overview

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2017
2017
Dephosphorylation of translation initiation factor 2 (eIF2α) terminates signalling in the mammalian integrated stress response… Expand
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2015
2015
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by loss of motor neurons. The… Expand
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Highly Cited
2014
Highly Cited
2014
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative disease characterized by the loss of motor… Expand
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Highly Cited
2013
Highly Cited
2013
C. elegans and D. rerio expressing mutant TAR DNA Binding Protein 43 (TDP-43) are powerful in vivo animal models for the genetics… Expand
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Highly Cited
2011
Highly Cited
2011
Guanabenz, a small-molecule inhibitor, protects cells from lethal accrual of misfolded proteins in the endoplasmic reticulum… Expand
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Highly Cited
2008
Highly Cited
2008
Background Prion-based diseases are incurable transmissible neurodegenerative disorders affecting animals and humans. Methodology… Expand
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Highly Cited
2004
Highly Cited
2004
SummaryAn elevated X-maze with alternating open and enclosed arms was investigated as a model for the study of fear-induced… Expand
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2003
2003
Objective To clarify the effects of bedtime administration of the centrally acting α2-agonists, guanabenz and clonidine, on… Expand
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Highly Cited
2000
Highly Cited
2000
The alpha-2 adrenergic receptor agonists, clonidine, lofexidine and guanabenz, blocked stress- but not cocaine-induced… Expand
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Highly Cited
1980
Highly Cited
1980
During norepinephrine release elecited by the arrival of nerve impulses, the neurotransmitter interacts with specific receptors… Expand
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