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glycylsarcosine

Known as: Gly-Sar 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Dipeptides

Papers overview

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Highly Cited
2012
Highly Cited
2012
The regulation of K‐ and L‐cell activity by GLUT2 and the calcium‐sensing receptor CasR in rat small intestine
•  In intestine, nutrients including glucose and amino acids and non‐nutrients including bile acids increase secretion of anti… Expand
Highly Cited
2010
Highly Cited
2010
Significance and Regional Dependency of Peptide Transporter (PEPT) 1 in the Intestinal Permeability of Glycylsarcosine: In Situ Single-Pass Perfusion Studies in Wild-Type and Pept1 Knockout Mice
The purpose of this study was to evaluate the role, relevance, and regional dependence of peptide transporter (PEPT) 1 expression… Expand
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Highly Cited
2003
Highly Cited
2003
Targeted Disruption of the PEPT2 Gene Markedly Reduces Dipeptide Uptake in Choroid Plexus*
The presence of multiple oligopeptide transporters in brain has generated considerable interest as to their physiological role in… Expand
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Highly Cited
2001
Highly Cited
2001
Epidermal growth factor inhibits glycylsarcosine transport and hPepT1 expression in a human intestinal cell line.
The human intestinal cell line Caco-2 was used as a model system to study the effects of epidermal growth factor (EGF) on peptide… Expand
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Highly Cited
2000
Highly Cited
2000
Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2.
In clinical trials, valganciclovir, the valyl ester of ganciclovir, has been shown to enhance the bioavailability of ganciclovir… Expand
Highly Cited
1998
Highly Cited
1998
Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.
Valacyclovir is a prodrug of the antiviral agent acyclovir and it does not contain a peptide bond in its structure. We studied… Expand
Highly Cited
1995
Highly Cited
1995
Differential Recognition of β-Lactam Antibiotics by Intestinal and Renal Peptide Transporters, PEPT 1 and PEPT 2 (*)
This study was initiated to determine if there are differences in the recognition of β-lactam antibiotics as substrates between… Expand
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Highly Cited
1993
Highly Cited
1993
Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H(+)-coupled carriers at both apical and basal membranes.
Glycylsarcosine (Gly-Sar) transport in human intestinal epithelial (Caco-2) cells has been investigated. Gly-Sar transport, from… Expand
Highly Cited
1984
Highly Cited
1984
Characteristics of glycylsarcosine transport in rabbit intestinal brush-border membrane vesicles.
Glycylsarcosine was found to be very resistant to hydrolysis by brush-border membrane vesicles from rabbit intestine. The… Expand
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Highly Cited
1972
Highly Cited
1972
Evidence for active transport of the dipeptide glycylsarcosine by hamster jejunum in vitro.
1. Glycylsarcosine, a peptide which is slowly hydrolysed by the intestine, is transported into the jejunal mucosal cells of the… Expand
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