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glycylsarcosine

Known as: Gly-Sar 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Dipeptides

Papers overview

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2010
2010
Significance and regional dependency of peptide transporter (PEPT) 1 in the intestinal permeability of glycylsarcosine: in situ single-pass perfusion studies in wild-type and Pept1 knockout mice.
The purpose of this study was to evaluate the role, relevance, and regional dependence of peptide transporter (PEPT) 1 expression… Expand
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Highly Cited
2005
Highly Cited
2005
Role and relevance of peptide transporter 2 (PEPT2) in the kidney and choroid plexus: in vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice.
The strategic localization of peptide transporter 2 (PEPT2), a proton-coupled oligopeptide transporter, to the apical membrane of… Expand
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2002
2002
Optimal absorptive transport of the dipeptide glycylsarcosine is dependent on functional Na+/H+ exchange activity
Abstract. Optimal nutrient absorption across the intestinal epithelium is dependent on the co-ordinated activity of a number of… Expand
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2001
2001
Epidermal growth factor inhibits glycylsarcosine transport and hPepT1 expression in a human intestinal cell line.
The human intestinal cell line Caco-2 was used as a model system to study the effects of epidermal growth factor (EGF) on peptide… Expand
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Highly Cited
2001
Highly Cited
2001
PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine.
Dietary proteins are mostly absorbed as di- and tripeptides by the intestinal proton-dependent transporter PepT1. We have… Expand
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Highly Cited
1998
Highly Cited
1998
Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.
Valacyclovir is a prodrug of the antiviral agent acyclovir and it does not contain a peptide bond in its structure. We studied… Expand
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Highly Cited
1995
Highly Cited
1995
Differential recognition of beta -lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2.
This study was initiated to determine if there are differences in the recognition of beta -lactam antibiotics as substrates… Expand
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Highly Cited
1993
Highly Cited
1993
Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H(+)-coupled carriers at both apical and basal membranes.
Glycylsarcosine (Gly-Sar) transport in human intestinal epithelial (Caco-2) cells has been investigated. Gly-Sar transport, from… Expand
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1993
1993
H(+)-coupled dipeptide (glycylsarcosine) transport across apical and basal borders of human intestinal Caco-2 cell monolayers display distinctive characteristics.
Transepithelial transport and intracellular accumulation of the dipeptide glycylsarcosine (Gly-Sar) were studied using intact… Expand
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1984
1984
Characteristics of glycylsarcosine transport in rabbit intestinal brush-border membrane vesicles.
Glycylsarcosine was found to be very resistant to hydrolysis by brush-border membrane vesicles from rabbit intestine. The… Expand
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