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glyceryl 2-arachidonate

Known as: 2-arachidonyl-glycerol, 5,8,11,14-eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (all-Z)-, 2-arachidonylglycerol 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (4)

Arachidonic AcidsCannabinoid Receptor AgonistsEndocannabinoidsGlycerides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Minireview: Endocannabinoids and their receptors as targets for obesity therapy.
As the incidence of obesity continues to increase, the development of effective therapies is a high priority. The endocannabinoid… 
Highly Cited
2008
Highly Cited
2008
COX-2 oxidative metabolism of endocannabinoids augments hippocampal synaptic plasticity
Review
2007
Review
2007
Therapeutic potential of endocannabinoid-hydrolysing enzyme inhibitors.
The specific protein target of delta9-tetrahydrocannabinol (delta9-THC), the main active ingredient of Cannabis sativa L., was… 
Highly Cited
2006
Highly Cited
2006
Neuropathic pain and the endocannabinoid system in the dorsal raphe: pharmacological treatment and interactions with the serotonergic system
We used a model of neuropathic pain consisting of rats with chronic constriction injury (CCI) of the sciatic nerve, in order to… 
Highly Cited
2005
Highly Cited
2005
Persistent anxiogenic effects of a single or repeated doses of cocaine and methamphetamine: interactions with endogenous cannabinoid receptor ligands
As persistent behavioural changes, such as increased anxiety-related behaviours, can be predicted based on the phenomenon of… 
Highly Cited
2004
Highly Cited
2004
1 DIFFERENTIAL EFFECTS OF ENDOGENOUS AND SYNTHETIC CANNABINOIDS ON α 7 -NICOTINIC ACETYLCHOLINE RECEPTOR-MEDIATED RESPONSES IN XENOPUS OOCYTES.
The effects of endogenous and synthetic cannabinoid receptor agonists including 2-arachidonoylglycerol, R-methanandamide, WIN55… 
Highly Cited
2003
Highly Cited
2003
An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors
At nanomolar concentrations, SR141716 and AM251 act as specific and selective antagonists of the cannabinoid CB1 receptor. In the… 
Review
2002
Review
2002
Endocannabinoid structure-activity relationships for interaction at the cannabinoid receptors.
Anandamide (N -arachidonoylethanolamine) was the first ligand to be identified as an endogenous ligand of the G-protein coupled… 
Highly Cited
2001
Highly Cited
2001
Activation of PAF receptors results in enhanced synthesis of 2‐arachidonoylglycerol (2‐AG) in immune cells
The endocannabinoid signaling system is believed to play a down‐regulatory role in the control of cell functions. However, little… 
Highly Cited
2001
Highly Cited
2001
Amino Acid Determinants in Cyclooxygenase-2 Oxygenation of the Endocannabinoid 2-Arachidonylglycerol*
The endocannabinoid, 2-arachidonylglycerol (2-AG), is an endogenous ligand for the central (CB1) and peripheral (CB2) cannabinoid… 
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