glyceryl 2-arachidonate

Known as: 2-arachidonyl-glycerol, 5,8,11,14-eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (all-Z)-, 2-arachidonylglycerol 
 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (4)

Arachidonic AcidsCannabinoid Receptor AgonistsEndocannabinoidsGlycerides

Papers overview

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Highly Cited
2009
Highly Cited
2009
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
2-Arachidonoylglycerol (2-AG) and anandamide are endocannabinoids that activate the cannabinoid receptors CB1 and CB2… (More)
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Highly Cited
2007
Highly Cited
2007
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol.
Endogenous ligands for cannabinoid receptors ("endocannabinoids") include the lipid transmitters anandamide and 2… (More)
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Highly Cited
2005
Highly Cited
2005
An endocannabinoid mechanism for stress-induced analgesia
Acute stress suppresses pain by activating brain pathways that engage opioid or non-opioid mechanisms. Here we show that an… (More)
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Highly Cited
2003
Highly Cited
2003
Nonpsychotropic cannabinoid receptors regulate microglial cell migration.
During neuroinflammation, activated microglial cells migrate toward dying neurons, where they exacerbate local cell damage. The… (More)
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Review
2003
Review
2003
Cannabis and the brain.
The active compound in herbal cannabis, Delta(9)-tetrahydrocannabinol, exerts all of its known central effects through the CB(1… (More)
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Highly Cited
2001
Highly Cited
2001
Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses
Marijuana affects brain function primarily by activating the G-protein-coupled cannabinoid receptor-1 (CB1), which is expressed… (More)
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Highly Cited
2000
Highly Cited
2000
Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2.
Cyclooxygenases (COX) play an important role in lipid signaling by oxygenating arachidonic acid to endoperoxide precursors of… (More)
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Highly Cited
1999
Highly Cited
1999
Dopamine activation of endogenous cannabinoid signaling in dorsal striatum
We measured endogenous cannabinoid release in dorsal striatum of freely moving rats by microdialysis and gas chromatography/mass… (More)
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Review
1999
Review
1999
The effects of cannabinoids on the brain
Cannabinoids have a long history of consumption for recreational and medical reasons. The primary active constituent of the hemp… (More)
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Highly Cited
1995
Highly Cited
1995
2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain.
The effects of anadamide, 2-arachidonoylglycerol and related compounds on the specific binding of a radiolabeled cannabinoid… (More)
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