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glutathione biosynthetic process
Known as:
glutathione formation
, glutathione biosynthesis
, glutathione anabolism
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The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for…
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National Institutes of Health
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Related topics
Related topics
3 relations
Narrower (1)
glutathione synthase activity
negative regulation of glutathione biosynthetic process
positive regulation of glutathione biosynthetic process
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress.
R. Vento
,
N. D’alessandro
,
M. Giuliano
,
M. Lauricella
,
M. Carabilló
,
G. Tesoriere
Experimental Eye Research
2000
Corpus ID: 24288779
Arachidonic acid administration caused apoptosis in Y79 cells, as shown by typical morphological changes, phosphatidylserine…
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Highly Cited
1998
Highly Cited
1998
Role of Endogenous Glutathione in the Oxidation of Dopamine
A. Rabinovic
,
T. Hastings
Journal of Neurochemistry
1998
Corpus ID: 20665619
Abstract: Intrastriatal injection of dopamine causes the selective degeneration of tyrosine hydroxylase‐containing terminals and…
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1998
1998
Development of glutathione synthesis and gamma-glutamyltranspeptidase activities in tissues from newborn infants.
J. Lavoie
,
P. Chessex
Free Radical Biology & Medicine
1998
Corpus ID: 46155399
Highly Cited
1998
Highly Cited
1998
Expression of Bcl-2 increases intracellular glutathione by inhibiting methionine-dependent GSH efflux.
M. Meredith
,
Carrie L. Cusick
,
S. R. Soltaninassab
,
Konjeti S. Sekhar
,
Shelly C. Lu
,
Michael L. Freeman
Biochemical and Biophysical Research…
1998
Corpus ID: 25403964
Overexpression of Bcl-2 and related anti-apoptotic gene products has been shown to increase the intracellular concentration of…
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Highly Cited
1996
Highly Cited
1996
Glutathione is an important antioxidant molecule in the yeast
D. Jamieson
1996
Corpus ID: 260635903
The tripeptide y-L-glutamyl+cystinylglycine (glutathione) is one of the major antioxidant molecules of cells and is thought to…
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Highly Cited
1989
Highly Cited
1989
Glutathione ester prevents buthionine sulfoximine-induced cataracts and lens epithelial cell damage.
Johannes Martensson
,
Reuben Steinherz
,
Ajey Jain
,
Alton Meister
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 32993798
Treatment of newborn rats and mice with buthionine sulfoximine, an inhibitor of glutathione synthesis, leads to development of…
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Highly Cited
1983
Highly Cited
1983
Turnover and functions of glutathione studied with isolated hepatic and renal cells.
S. Orrenius
,
K. Ormstad
,
H. Thor
,
S. Jewell
Federation proceedings
1983
Corpus ID: 41418844
Suspensions of freshly isolated rat hepatocytes and renal tubular cells contain high levels of reduced glutathione (GSH), which…
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Highly Cited
1983
Highly Cited
1983
Enhancement of misonidazole radiosensitization by an inhibitor of glutathione biosynthesis.
R. Hodgkiss
,
R. Middleton
International Journal of Radiation Biology and…
1983
Corpus ID: 31571020
Highly Cited
1982
Highly Cited
1982
Effect of selenium deficiency and vitamin E deficiency on glutathione metabolism in isolated rat hepatocytes.
K. Hill
,
R. Burk
Journal of Biological Chemistry
1982
Corpus ID: 19884038
Highly Cited
1970
Highly Cited
1970
Glutathione synthetase deficiency as a cause of hereditary hemolytic disease.
D. Mohler
,
P. Majerus
,
V. Minnich
,
C. Hess
,
M. Garrick
New England Journal of Medicine
1970
Corpus ID: 30890146
Abstract Two enzymes are required for de novo glutathione synthesis: glutamyl-cysteine synthetase and glutathione synthetase. In…
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