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glutamine biosynthetic process

Known as: glutamine anabolism, glutamine biosynthesis, glutamine synthesis 
The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid. [GOC:ai]
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Chronic and acute ammonia toxicity in mudskippers, Periophthalmodon schlosseri and Boleophthalmus boddaerti: brain ammonia and glutamine contents, and effects of methionine sulfoximine and MK801
SUMMARY The objective of this study was to elucidate if chronic and acute ammonia intoxication in mudskippers, Periophthalmodon… 
Highly Cited
1999
Highly Cited
1999
Accelerated glutamine synthesis in critically ill patients cannot maintain normal intramuscular free glutamine concentration.
BACKGROUND Muscle glutamine is severely depleted in critically ill patients (by approximately 50% to 80% of normal). Because… 
Highly Cited
1994
Highly Cited
1994
Glutamine kinetics in burn patients. Comparison with hormonally induced stress in volunteers.
OBJECTIVE To assess the acute and protracted adaptive response of peripheral glutamine kinetics to a severe injury. DESIGN… 
Highly Cited
1992
Highly Cited
1992
Restoration of cerebrovascular CO2 responsivity by glutamine synthesis inhibition in hyperammonemic rats.
Hyperammonemia increases brain glutamine levels, causes astrocytic swelling, and depresses cerebral blood flow (CBF) responsivity… 
Highly Cited
1983
Highly Cited
1983
Hepatocyte heterogeneity in glutamate uptake by isolated perfused rat liver.
Glutamate is simultaneously taken up and released by perfused rat liver, as shown by 14CO2 production from [1-14C]glutamate in… 
Highly Cited
1977
Highly Cited
1977
Acid‐base induced alterations in glutamine metabolism and ureogenesis in perfused muscle and liver of the rat
Abstract. The effects of altered acid‐base balance on the production of urea and the metabolism of glutamine were investigated in… 
Highly Cited
1975
Highly Cited
1975
Kinetics and Energetics of Light-driven Chloroplast Glutamine Synthesis.
Chloroplasts contain the enzyme glutamine synthetase. Formation of glutamine by isolated chloroplasts is light-dependent and… 
Highly Cited
1973
Highly Cited
1973
Studies on glutamine synthetase from Escherichia coli. Formation of pyrrolidone carboxylate and inhibition by methionine sulfoximine.
Abstract Both the adenylylated and unadenylylated forms of Escherichia coli glutamine synthetase catalyze the formation of… 
Highly Cited
1971
Highly Cited
1971
Control of glutamine synthesis in rat liver.
1. On perfusion of livers from fed rats with a semi-synthetic medium containing no added amino acids there is a rapid release of… 
Highly Cited
1970
Highly Cited
1970
Multiple molecular forms of glutamine synthetase produced by enzyme catalyzed adenylation and deadenylylation reactions.
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