glucagon secretion

The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans). [GOC:BHF, GOC:rl]
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Type 2 diabetes (T2D) is characterized by chronic hyperglycemia resulting from a deficiency in insulin signaling, because of… (More)
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Review
2011
Review
2011
Excessive production of glucose by the liver contributes to fasting and postprandial hyperglycaemia, hallmarks of type 2 diabetes… (More)
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Highly Cited
2009
Highly Cited
2009
Glucagon plays an important role in glucose homeostasis by regulating hepatic glucose output in both normo- and hypoglycemic… (More)
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Review
2006
Review
2006
Glucagon-like peptide 1 (GLP-1) is a gut-derived incretin hormone that stimulates insulin and suppresses glucagon secretion… (More)
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Highly Cited
2006
Highly Cited
2006
The mechanisms by which glucose regulates glucagon release are poorly understood. The present study aimed to clarify the direct… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS The gut-derived peptide glucagon-like peptide 2 (GLP-2) has been suggested as a potential drug candidate for… (More)
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Highly Cited
2005
Highly Cited
2005
Ripglut1;glut2-/- mice have no endogenous glucose transporter type 2 (glut2) gene expression but rescue glucose-regulated insulin… (More)
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Highly Cited
2004
Highly Cited
2004
GLP-1 stimulates insulin secretion, suppresses glucagon secretion, delays gastric emptying, and inhibits small bowel motility… (More)
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Highly Cited
2003
Highly Cited
2003
In the isolated perfused pancreas, gastric inhibitory polypeptide (GIP) has been shown to enhance glucagon secretion at basal… (More)
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Highly Cited
1989
Highly Cited
1989
THE endocrine part of the pancreas plays a central role in blood-glucose regulation. It is well established that an elevation of… (More)
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