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globotriaosylceramide

Known as: Ganglioside GA3, O-alpha-D-galactopyranosyl-(1-4B)-, Gal-1-4-Gal-1-4-Glc-cer, P(K) antigen 
National Institutes of Health

Related topics

Related topics

2 relations
CD77 antigen

Broader (1)

Trihexosylceramides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells
Previous studies demonstrated that certain glycosphingolipids (GSLs) are involved in various cell functions, such as cell growth… 
Highly Cited
2012
Highly Cited
2012
Ceramide Glycosylation by Glucosylceramide Synthase Selectively Maintains the Properties of Breast Cancer Stem Cells*
Background: Glucosylceramide synthase catalyzes ceramide glycosylation that regulates the synthesis of glycosphingolipids… 
Highly Cited
2010
Highly Cited
2010
The pharmacological chaperone 1-deoxygalactonojirimycin reduces tissue globotriaosylceramide levels in a mouse model of Fabry disease.
Fabry disease is an X-linked lysosomal storage disorder caused by a deficiency in alpha-galactosidase A (alpha-Gal A) activity… 
Highly Cited
2007
Highly Cited
2007
Heterooligomerization between vasotocin and corticotropin-releasing hormone (CRH) receptors augments CRH-stimulated 3',5'-cyclic adenosine monophosphate production.
In birds, ACTH release from the anterior pituitary gland during stress is controlled by CRH and arginine vasotocin (AVT). Using 5… 
Highly Cited
2000
Highly Cited
2000
Reduction of globotriaosylceramide in Fabry disease mice by substrate deprivation.
We used a potent inhibitor of glucosylceramide synthase to test whether substrate deprivation could lower globotriaosylceramide… 
Highly Cited
1994
Highly Cited
1994
Interaction of the Shiga-like toxin type 1 B-subunit with its carbohydrate receptor.
A study of the binding of the Shiga-like toxin 1 (SLT-1) to the P(k) trisaccharide [methyl 4-O-(4-O-alpha-D-galactopyranosyl)-4-O… 
Highly Cited
1990
Highly Cited
1990
Induction of verotoxin sensitivity in receptor-deficient cell lines using the receptor glycolipid globotriosylceramide.
Verotoxin 1 is an Escherichia coli-derived subunit toxin that specifically binds to the glycolipid globotriosylceramide and is… 
Highly Cited
1990
Highly Cited
1990
Expression of glycolipid receptors to Shiga-like toxin on human B lymphocytes: a mechanism for the failure of long-lived antibody response to dysenteric disease.
Fresh and transformed human B lineage cells were found to be sensitive to the cytotoxic action of Shiga-like toxin (SLT), a… 
Highly Cited
1988
Highly Cited
1988
Lipid composition of PC12 pheochromocytoma cells: characterization of globoside as a major neutral glycolipid.
We have studied the lipid composition of PC12 pheochromocytoma cells cultured in the presence and absence of nerve growth factor… 
Highly Cited
1987
Highly Cited
1987
Roles of globotriosyl- and galabiosylceramide in verotoxin binding and high affinity interferon receptor.
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