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gliquidone

Known as: N-(Cyclohexylcarbamoyl)-4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl)ethyl]benzenesulfonamide, glikvidon, glycvidon 
A potent, second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, gliquidone exerts greater binding… 
National Institutes of Health

Related topics

Related topics

6 relations

Narrower (3)

BeglynorGlurenorGlurenorm
Gliquidone:MCnc:Pt:Ser/Plas:Qn

Broader (2)

Hypoglycemic AgentsSulfonylurea Compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
RP-LC method for the simultaneous determination of gliquidone, pioglitazone hydrochloride, and atorvastatin in formulations and human serum.
The objective of this research was to develop and validate a rapid, economical, and sensitive HPLC method for quantitative… 
2010
2010
Drug interaction studies of gliquidone with fexofenadine, cetirizine, and levocetirizine
Controlling blood sugar levels is crucial for diabetic patients and is managed through administration of drugs such as gliquidone… 
Highly Cited
2008
Highly Cited
2008
Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction.
2003
2003
Hydroxyl-substituted sulfonylureas as potent inhibitors of specific [3H]glyburide binding to rat brain synaptosomes.
1998
1998
Sulfonylurea effects on acid and pepsinogen secretion in isolated rabbit gastric glands.
1997
1997
Inhibiting effects of antioxidants on drug-induced phototoxicity in cell cultures. Investigations with sulphonamide-derived oral antidiabetics and diuretics.
1996
1996
Effects of galanin on 8-OH-DPAT induced decrease in body temperature and brain 5-hydroxytryptamine metabolism in the mouse.
1994
1994
Hypothermia induced by cholinomimetic drugs is blocked by galanin: possible involvement of ATP-sensitive K+ channels.
1979
1979
Extrapancreatic action of sulphonylureas: effect of gliquidone on insulin and glucagon binding to rat liver plasma membranes
Abstract. Gliquidone (a second generation sulphonylurea) was administered orally to normal rats 1 h before killing. Gliquidone… 
1979
1979
Effect of two sulphonylureas on the dose kinetics of glucose-induced insulin release in normal and diabetic subjects.
The effect of two second generation sulphonylureas, gliquidone and glibenclamide, on insulin secretion has been studied in the… 
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