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gliquidone

Known as: N-(Cyclohexylcarbamoyl)-4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl)ethyl]benzenesulfonamide, glikvidon, glycvidon 
A potent, second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, gliquidone exerts greater binding… 
National Institutes of Health

Related topics

Related topics

6 relations

Narrower (3)

BeglynorGlurenorGlurenorm
Gliquidone:MCnc:Pt:Ser/Plas:Qn

Broader (2)

Hypoglycemic AgentsSulfonylurea Compounds

Papers overview

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Highly Cited
2008
Highly Cited
2008
Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction.
2004
2004
Diabetic control with gliquidone — A short acting sulphonylurea
SummaryGliquidone (Glurenorm) and glibenclamide were compared in a cross-over study of 20 non insulin dependent diabetics. Both… 
1999
1999
Pharmacokinetics of gliquidone, glibenclamide, gliclazide and glipizide in middle-aged and aged subjects.
Six middle-aged (42-59 years old) and six aged (71-75 years old) subjects received each, on separate days, an oral administration… 
1997
1997
Evaluation of phototoxic properties of oral antidiabetics and diuretics. Photohemolysis model as a screening method for recognizing potential photosensitizing drugs.
The oral hypoglycemic drugs carbutamide, chlorpropamide, glibenclamide, glubornuride, gliclazide, glipizide, gliquidone… 
1994
1994
Glucose modulates the amount, but not the kinetics, of insulin released by sulfonylureas.
1993
1993
Sulfonylureas activate glycogen phosphorylase and increase cytosolic free-Ca2+ levels in isolated rat hepatocytes.
1990
1990
Evidence for more than One Binding Site for Sulfonylureas in Insulin‐secreting Cells
Abstract— Specific binding of both [3H]glibenclamide and [3H]gliquidone has been observed in a particulate fraction of insulin… 
1984
1984
Extrapancreatic action of the sulphonylurea gliquidone: post-receptor effect on insulin-stimulated glycogen synthesis in rat hepatocytes in primary culture
SummaryThe effects of a sulphonylurea, gliquidone, on insulin binding and the insulin induced rate of glycogen synthesis, were… 
1979
1979
Extrapancreatic action of sulphonylureas: effect of gliquidone on insulin and glucagon binding to rat liver plasma membranes
Abstract. Gliquidone (a second generation sulphonylurea) was administered orally to normal rats 1 h before killing. Gliquidone… 
1979
1979
Effect of two sulphonylureas on the dose kinetics of glucose-induced insulin release in normal and diabetic subjects.
The effect of two second generation sulphonylureas, gliquidone and glibenclamide, on insulin secretion has been studied in the… 
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