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glatiramer acetate
Known as:
COP-1
, L-Glutamic acid peptide with L-alanine, L-lysine and L-tyrosine, acetate (salt)
, Copolymer-1
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A random polymer of L-ALANINE, L-GLUTAMIC ACID, L-LYSINE, and L-TYROSINE that structurally resembles MYELIN BASIC PROTEIN. It is used in the…
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National Institutes of Health
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Related topics
Related topics
21 relations
1 ML glatiramer acetate 40 MG/ML Prefilled Syringe [Copaxone]
Drug Allergy
In Blood
Multiple Sclerosis, Relapsing-Remitting
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Broader (4)
Antirheumatic Agents
Glatiramer
Immunologic Adjuvants
Immunosuppressive Agents
Narrower (3)
Copaxone
Glatopa
TV 5010
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Relapse Rates in Patients with Multiple Sclerosis Switching from Interferon to Fingolimod or Glatiramer Acetate: A US Claims Database Study
N. Bergvall
,
C. Makin
,
+7 authors
J. Korn
PLoS ONE
2014
Corpus ID: 1735415
Background Approximately one-third of patients with multiple sclerosis (MS) are unresponsive to, or intolerant of, interferon…
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Review
2010
Review
2010
Glatiramer acetate for multiple sclerosis.
L. La Mantia
,
L. Munari
,
R. Lovati
Cochrane Database of Systematic Reviews
2010
Corpus ID: 205174886
BACKGROUND This is an updated Cochrane review of the previous version published (Cochrane Database of Systematic Reviews 2004…
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Highly Cited
2007
Highly Cited
2007
Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis reveals drug-response markers
I. Grossman
,
N. Avidan
,
+9 authors
Ariel Miller
Pharmacogenetics & Genomics
2007
Corpus ID: 33424236
Genetic-based optimization of treatment prescription is becoming a central research focus in the management of chronic diseases…
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Highly Cited
2006
Highly Cited
2006
Sequential maintenance treatment with glatiramer acetate after mitoxantrone is safe and can limit exposure to immunosuppression in very active, relapsing remitting multiple sclerosis
J. Ramtahal
,
A. Jacob
,
K. Das
,
M. Boggild
Journal of Neurology
2006
Corpus ID: 15901340
Mitoxantrone has been approved by the FDA for worsening relapsing remitting and secondary progressive Multiple Sclerosis. However…
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Highly Cited
2002
Highly Cited
2002
Thermoplastic elastomer hydrogels via self-assembly of an elastin-mimetic triblock polypeptide
E. Wright
,
R. Mcmillan
,
A. Cooper
,
R. Apkarian
,
V. Conticello
2002
Corpus ID: 10718777
Synthetic polymers consisting of well-defined blocks of compositionally dissimilar monomers undergo microscopic phase separation…
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Highly Cited
2001
Highly Cited
2001
HLA-DRB1*1501 and response to copolymer-1 therapy in relapsing-remitting multiple sclerosis
C. Fusco
,
V. Andreone
,
+12 authors
M. Lombardi
Neurology
2001
Corpus ID: 45275171
Background: Copolymer 1 (Cop-1) is a random synthetic amino acid copolymer, effective in the treatment of the relapsing-remitting…
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Review
1999
Review
1999
The Decade of Autoimmunity
Y. Shoenfeld
1999
Corpus ID: 68518126
Highly Cited
1997
Highly Cited
1997
New treatments and azathioprine in multiple sclerosis
J. Palace
,
P. Rothwell
The Lancet
1997
Corpus ID: 11751308
Highly Cited
1996
Highly Cited
1996
The autoimmune reactivity to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis is potentially pathogenic: Effect of copolymer 1 on MOG-induced disease
A. Ben-nun
,
Itzhack Mendel
,
+5 authors
N. Rosbo
Journal of Neurology
1996
Corpus ID: 22404260
Multiple sclerosis (MS), an autoimmune disease of the central nervous system (CNS) characterized by primary demyelination, is…
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Highly Cited
1983
Highly Cited
1983
Effect of treatment with copolymer 1 (Cop-1) on the in vivo and in vitro manifestations of experimental allergic encephalomyelitis (EAE)
R. Lisak
,
B. Zweiman
,
N. Blanchard
,
L. Rorke
Journal of Neurological Sciences
1983
Corpus ID: 25828553
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