glatiramer acetate

Known as: COP-1, L-Glutamic acid peptide with L-alanine, L-lysine and L-tyrosine, acetate (salt), Copolymer-1 
A random polymer of L-ALANINE, L-GLUTAMIC ACID, L-LYSINE, and L-TYROSINE that structurally resembles MYELIN BASIC PROTEIN. It is used in the… (More)

Topic mentions per year

Topic mentions per year

1988-2018
05010019882018

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND BG-12 (dimethyl fumarate) is in development as an oral treatment for relapsing-remitting multiple sclerosis, which is… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Glatiramer acetate, approved for the treatment of relapsing-remitting multiple sclerosis, reduces relapses and disease… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Interferon beta-1a and glatiramer acetate are commonly prescribed for relapsing-remitting multiple sclerosis (RRMS… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To determine whether glatiramer acetate (GA) slows accumulation of disability in primary progressive multiple sclerosis… (More)
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Highly Cited
2006
Highly Cited
2006
Alzheimer's disease (AD) is characterized by plaque formation, neuronal loss, and cognitive decline. The functions of the local… (More)
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Highly Cited
2004
Highly Cited
2004
Glatiramer acetate (GA) therapy of patients with multiple sclerosis (MS) represents a unique setting in which in vivo Th2… (More)
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Highly Cited
2001
Highly Cited
2001
Two prior double-blind, placebo-controlled, randomized trials demonstrated that glatiramer acetate (GA) reduces relapse rates in… (More)
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Highly Cited
2000
Highly Cited
2000
We examined the effect of glatiramer acetate, a random copolymer of alanine, lysine, glutamic acid, and tyrosine, on antigen… (More)
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2000
2000
OBJECTIVE To define the mechanism of action of glatiramer acetate (GA; formerly known as copolymer-1) as an immunomodulatory… (More)
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Highly Cited
1995
Highly Cited
1995
We studied copolymer 1 (Copaxone) in a multicenter (11-university) phase III trial of patients with relapsing-remitting multiple… (More)
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