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International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
TLDR
This document appraise the existing evidence on clinical and laboratory features of APS addressed during the forum and proposes amendments to the Sapporo criteria, including definitions on features ofAPS that were not included in the updated criteria. Expand
Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients.
TLDR
An association with SLE, the patient's sex, and the patient’s age at disease onset can modify the disease expression and define specific subsets of APS. Expand
'ASIA' - autoimmune/inflammatory syndrome induced by adjuvants.
TLDR
The current data regarding the role of adjuvants in the pathogenesis of immune mediated diseases as well as the amassed data regarding each of these four conditions are reviewed to suggest to include these comparable conditions under a common syndrome entitled ASIA, "Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants". Expand
Pathogenesis and natural history of osteonecrosis.
TLDR
The understanding of the pathogenesis of osteonecrosis is now much better defined and skeletal scintigraphy and magnetic resonance imaging have enhanced diagnosis greatly, helping the physician determine which patients are at risk for oste onecrosis, facilitating early diagnosis and better treatment options. Expand
Effects of tobacco smoke on immunity, inflammation and autoimmunity.
TLDR
The current review underlines the importance of smoking prevention and eradication not only in respiratory disorders but also in autoimmune conditions as well. Expand
Catastrophic antiphospholipid syndrome: international consensus statement on classification criteria and treatment guidelines
TLDR
Anticoagulation, corticosteroids, plasma exchange, intravenous gammaglobulins and, if associated with lupus flare, cyclophosphamide, are the most commonly used treatments for catastrophic APS patients. Expand
Obesity in autoimmune diseases: not a passive bystander.
TLDR
Obesity appears to be a major environmental factor contributing to the onset and progression of autoimmune diseases. Expand
Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-a review of recent evidence.
TLDR
Adequate vitamin D supplementation and sensible sunlight exposure to reach optimal vitamin D status are among the front line factors of prophylaxis for the spectrum of disorders. Expand
EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases
TLDR
Recommendations for vaccination in patients with AIIRD based on the currently available evidence and expert opinion were formulated, and more research is needed, particularly regarding the incidence of vaccine-preventable infectious diseases and the safety of vaccination in Patients with A IIRD. Expand
Anti-inflammatory and immunosuppressive drugs and reproduction
TLDR
Benefits of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed. Expand
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