FAQ

ganglioside catabolic process

Known as: ganglioside breakdown, ganglioside catabolism, ganglioside degradation 
The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2015
01219732015

Papers overview

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2010
2010
Regulation of plasma-membrane-associated sialidase NEU3 gene by Sp1/Sp3 transcription factors.
Gene expression of the human plasma membrane-associated sialidase (NEU3), a key enzyme for ganglioside degradation, is relatively… (More)
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2008
2008
Mice deficient in Neu4 sialidase exhibit abnormal ganglioside catabolism and lysosomal storage.
Mammalian sialidase Neu4, ubiquitously expressed in human tissues, is located in the lysosomal and mitochondrial lumen and has… (More)
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2007
2007
A crucial role of plasma membrane-associated sialidase in the survival of human cancer cells
Human plasma membrane-associated sialidase (NEU3), a key enzyme for ganglioside degradation, is markedly upregulated in human… (More)
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2005
2005
Enhanced GM1 ganglioside catabolism in cultured fibroblasts from Alzheimer patients.
The metabolic processing of GM1 ganglioside, exogenously administered to cultured skin fibroblasts, was investigated on cells… (More)
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1997
1997
Evidence for the involvement of Glu-355 in the catalytic action of human beta-hexosaminidase B.
In a previous study the photoactivable affinity probe, 3-azi-1-[([6-3H]2-acetamido-2-deoxy-1-beta-D-galactopyranosyl)thio ]-b… (More)
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Highly Cited
1995
Highly Cited
1995
Mouse models of Tay–Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism
Tay–Sachs and Sandhoff diseases are clinically similar neurodegenerative disorders. These two sphingolipidoses are characterized… (More)
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1994
1994
Modulation of the activity of Clostridium perfringens neuraminidase by the molecular organization of gangliosides in monolayers.
The activity of Clostridium perfringens neuraminidase against gangliosides GM3, GD1a and GM1 was studied in lipid monolayers at… (More)
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1986
1986
Regulation of liver cell ganglioside composition by extracellular fluid viscosity
The viscosity of plasma and extracellular fluid has been shown to be a regulator of lipoprotein production both in cultured… (More)
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1985
1985
The influence of ganglioside insertion into brain membranes on the rate of ganglioside degradation by membrane-bound sialidase.
Microsomal membranes isolated from calf brain contain a sialidase which cleaves ganglioside substrates naturally occurring within… (More)
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1973
1973
Ocular pathology of GM2 gangliosidosis--Type 2 (Sandhoff's disease).
The introduction in recent years of more refined techniques for the isolation and characterization of biological lipids has led… (More)
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