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ganaxolone

Known as: 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one 
 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Mood disorders represent the largest cause of disability worldwide. The monoaminergic deficiency hypothesis, which has dominated… Expand
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Review
2018
Review
2018
The Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV) took place in Madrid, Spain, on May 13‐16… Expand
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Review
2015
Review
2015
The Twelfth Eilat Conference on New Antiepileptic Drugs (AEDs) - EILAT XII, took place in Madrid, Spain from August 31st to… Expand
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Highly Cited
2010
Highly Cited
2010
Fragile X syndrome is the most common heritable form of mental retardation. It is caused by silencing of the Fmr1 gene and the… Expand
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Review
2007
Review
2007
  • A. Morrow
  • Pharmacology & therapeutics
  • 2007
  • Corpus ID: 9952773
This special issue heralds an exciting time in the field when the significance of neuroactive steroids in the regulation of… Expand
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Review
2006
Review
2006
There is a remarkable array of new chemical entities in the current antiepileptic drug (AED) development pipeline. In some cases… Expand
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Highly Cited
2004
Highly Cited
2004
Summary:  Purpose: Low‐frequency (6 Hz), long‐duration (3 s) electrical stimulation in mice produces seizures characterized by… Expand
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Highly Cited
1997
Highly Cited
1997
Ganaxolone (CCD 1042) is a 3b-methyl-substituted analog of the endogenous neuroactive steroid 3a-hydroxy-5a-pregnan20-one… Expand
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Highly Cited
1997
Highly Cited
1997
Summary: Purpose: Studies were conducted to establish the safety, tolerability, and pharmacokinetics of the antiepileptic drug… Expand
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Highly Cited
1977
Highly Cited
1977
Described herein are the chemical syntheses of 5alpha-cholest-8(14-en-3beta-ol-15-one, 14alpha-methyl-5alpha-cholest-7-en-3beta… Expand
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