ganaxolone

Known as: 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one 
 
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
OBJECTIVE Minocycline rescued synaptic abnormalities and improved behavior in the fragile X mouse model. Previous open-label… (More)
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2010
2010
Ganaxolone (3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a synthetic analog of the endogenous neurosteroid… (More)
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2007
2007
PURPOSE A pilot study of the safety, tolerability, dose range and potential efficacy of ganaxolone for the treatment of… (More)
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2000
2000
PURPOSE A double-blind, randomized, placebo-controlled clinical trial to examine the safety, tolerability, and antiepileptic… (More)
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2000
2000
This is a multicenter, open-label, add-on trial, investigating the safety and efficacy of ganaxolone (GNX) in a population of… (More)
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2000
2000
Perimenstrual catamenial epilepsy, the exacerbation of seizures in association with menstruation, may in part be due to… (More)
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2000
2000
Ganaxolone (3alpha-hydroxy-3beta-methyl-5alpha-pregnane-20-one), an orally active synthetic analog of the neuroactive steroid… (More)
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2000
2000
PURPOSE To determine the effects of a newly synthesized epalon, ganaxolone (GNX), on primarily generalized seizures in rats of… (More)
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1998
1998
Neuroactive steroids are naturally occurring or synthetically derived compounds many of which have anticonvulsant, anesthetic… (More)
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1997
1997
PURPOSE Studies were conducted to establish the safety, tolerability, and pharmacokinetics of the antiepileptic drug (AED… (More)
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