gamma-Glutamyltransferase deficiency

The degradation pathway of glutathione (GSH) in plants is not well understood. In mammals, GSH is predominantly metabolized… Expand

Glutathione is a tripeptide composed of glutamate, cysteine and glycine. Glutathione is present in millimolar concentrations in… Expand

A mentally retarded young woman with severe behaviour problems was found to excrete large amounts of glutathione due to a… Expand

SummaryWe report on two Japanese brothers with hereditary deficiency in γ-glutamyl transpeptidase. The propositus was 48 years… Expand

A mouse mutant with glutathionuria was discovered by screening for amino acidurias in the progeny of ethylnitrosourea-mutagenized… Expand

Treatment of mice with various gamma-glutamyl amino acids leads to marked urinary excretion of glutathione and other gamma… Expand

The catabolism of glutathione in various nonrenal tissues occurs through an interorgan process [ 1,2]. For example, the turnover… Expand

The indication of ornithine decarboxylase (ODC) by barbiturates and the ability of barbiturates to enhance neoplastic progression… Expand

Rat renal gamma-glutamyltranspeptidase is an intrinsic membrane glycoprotein. The larger of its two subunits is apparently folded… Expand

Summary A patient has been discovered with glutathionemia and marked glutathionuria. Serum concentrations of individual… Expand