• Publications
  • Influence
Biologic and pharmacologic regulation of mammalian glutathione synthesis.
  • O. Griffith
  • Biology, Chemistry
    Free radical biology & medicine
  • 1 November 1999
Mammalian nitric oxide synthases.
The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase.
TLDR
The key step in glutathione synthesis, namely the ATP-dependent synthesis of gamma-glutamylcysteine, is the topic of this review and attention is focused on post-translational regulation.
Mammalian sulfur amino acid metabolism: an overview.
Glutathione: interorgan translocation, turnover, and metabolism.
  • O. Griffith, A. Meister
  • Biology, Chemistry
    Proceedings of the National Academy of Sciences…
  • 1 November 1979
TLDR
The present and earlier findings lead to a tentative scheme for the metabolism and translocation of glutathione, gamma-glutamyl amino acids, and related compounds.
Origin and turnover of mitochondrial glutathione.
Mitochondrial glutathione in liver does not arise by intramitochondrial synthesis, but rather from the cytoplasm, by a process characterized by slow net transport and more rapid exchange transport.
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