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flobufen

Known as: 4-(2,4-difluorbiphenylyl)-4-oxo-2-methylbutanoic acid 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Butyrates

Narrower (1)

VUFB 16066

Papers overview

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2006
2006
Synthesis and Enhancing Effect of Transkarbam 12 on the Transdermal Delivery of Theophylline, Clotrimazole, Flobufen, and Griseofulvin
PurposeDodecyl-6-aminohexanoate (DDEAC) is a transdermal permeation enhancer with excellent activity, low toxicity, and no dermal… 
Highly Cited
2005
Highly Cited
2005
Comparison of vancomycin-based stationary phases with different chiral selector coverage for enantioselective separation of selected drugs in high-performance liquid chromatography.
2003
2003
Stereoselective pharmacokinetics and metabolism of flobufen in guinea pigs.
Stereoselective aspects of pharmacokinetics and metabolism of a chiral nonsteroidal antiinflammatory drug, flobufen, 4-(2', 4… 
2001
2001
Stereospecificity and stereoselectivity of flobufen metabolic profile in male rats in vitro and in vivo: phase I of biotransformation.
Flobufen (F) is the original nonsteroidal antiinflammatory drug (NSAID) containing two enantiomers. The aim of this investigation… 
2001
2001
Enantioseparation of Flobufen with Cyclodextrins Studied by Capillary Electrophoresis and NMR
AbstractPurpose. The aim of this study was to obtain the resolution of flobufen enantiomers, an antiinflammatory active substance… 
1999
1999
Stereoselective pharmacokinetics of flobufen in rats.
Stereoselectivity of the pharmacokinetics of the nonsteroidal anti-inflammatory drug flobufen, 4-(2', 4'-difluorobiphenyl-4-yl)-2… 
1999
1999
Direct resolution of optically active isomers on chiral packings containing ergoline skeleton. 6. Enantioseparation of profens.
The enantioselective behaviour of some underivatized 2-arylpropionic acids (profens) and flobufen by HPLC using a terguride-based… 
1997
1997
Chiral resolution of flobufen by high performance liquid chromatography and capillary electrophoresis.
The enantiomeric separation of an anti-inflammatory drug flobufen was performed on various chiral columns in liquid… 
1997
1997
Electrokinetic separation of enantiomers using a capillary coated with poly-terguride.
Enantioseparation of 2-arylpropionic acids (Flobufen) and dansyl-derivatives of amino acids can be achieved in 10-15 min by… 
1990
1990
Pharmacokinetics of flobufen and its main active metabolite in the rat.
Pharmacokinetic study of the anti-inflammatory [3H] flobufen (I) and its active metabolite (II) has been carried out in rats… 
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