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fibroblast apoptotic process
Known as:
fibroblast apoptosis
Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. [CL…
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National Institutes of Health
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Highly Cited
2019
Highly Cited
2019
Bone marrow fibroblasts overexpress miR‐27b and miR‐214 in step with multiple myeloma progression, dependent on tumour cell‐derived exosomes
M. Frassanito
,
V. Desantis
,
+19 authors
A. Vacca
Journal of Pathology
2019
Corpus ID: 53029974
Aberrant microRNA (miR) expression has an important role in tumour progression, but its involvement in bone marrow fibroblasts of…
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Highly Cited
2016
Highly Cited
2016
CD11c+ CD8+ T Cells Reduce Renal Fibrosis Following Ureteric Obstruction by Inducing Fibroblast Apoptosis
Haidong Wang
,
Juan Wang
,
Yun-Qing Bai
,
Jinwei Li
,
Lixin Li
,
Yanjun Dong
International Journal of Molecular Sciences
2016
Corpus ID: 17597134
Tubulointerstitial fibrosis is a common consequence of various kidney diseases that lead to end-stage renal failure, and…
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Highly Cited
2010
Highly Cited
2010
Impaired wound healing in mouse models of diabetes is mediated by TNF-α dysregulation and associated with enhanced activation of forkhead box O1 (FOXO1)
Michelle F. Siqueira
,
Jingyuan Li
,
+8 authors
D. Graves
Diabetologia
2010
Corpus ID: 206872682
Aims/hypothesisThe role of TNF-α in impaired wound healing in diabetes was examined by focusing on fibroblasts.MethodsSmall…
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Highly Cited
2009
Highly Cited
2009
Prostaglandin E2 induces fibroblast apoptosis by modulating multiple survival pathways
Steven K. Huang
,
E. White
,
+5 authors
M. Peters-Golden
The FASEB Journal
2009
Corpus ID: 25073379
Although the lipid mediator prostaglandin E2 (PGE2) exerts antifibrotic effects by inhibiting multiple fibroblast functions, its…
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Highly Cited
2009
Highly Cited
2009
1alpha,25(OH)2D3 and its 3-epimer promote rat lung alveolar epithelial-mesenchymal interactions and inhibit lipofibroblast apoptosis.
R. Sakurai
,
E. Shin
,
+5 authors
V. Rehan
American Journal of Physiology - Lung cellular…
2009
Corpus ID: 9015115
Although alveolar wall thinning has been attributed to apoptosis of interstitial lung lipofibroblasts (LFs), the underlying…
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Highly Cited
2008
Highly Cited
2008
Loss of Macroautophagy Promotes or Prevents Fibroblast Apoptosis Depending on the Death Stimulus*♦
Yongjun Wang
,
Rajat Singh
,
+6 authors
M. Czaja
Journal of Biological Chemistry
2008
Corpus ID: 40210487
Macroautophagy has been implicated as a mechanism of cell death. However, the relationship between this degradative pathway and…
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Highly Cited
2005
Highly Cited
2005
FOXO1 Functions as a Master Switch That Regulates Gene Expression Necessary for Tumor Necrosis Factor-induced Fibroblast Apoptosis*
M. Alikhani
,
Z. Alikhani
,
D. Graves
Journal of Biological Chemistry
2005
Corpus ID: 42584445
Tumor necrosis factor-α (TNF-α) is a potent pro-inflammatory and pro-apoptotic mediator that plays an important role in several…
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Highly Cited
2000
Highly Cited
2000
Induction of lung fibroblast apoptosis by soluble fibronectin peptides.
Hélène Levrey Hadden
,
C. Henke
American Journal of Respiratory and Critical Care…
2000
Corpus ID: 7256783
Despite the importance of fibroproliferative lung disorders, no safe and effective therapies exist for reducing the size of the…
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Highly Cited
1999
Highly Cited
1999
Lovastatin induces fibroblast apoptosis in vitro and in vivo. A possible therapy for fibroproliferative disorders.
A. Tan
,
H. Levrey
,
Cornelia Dahm
,
V. Polunovsky
,
J. Rubins
,
P. Bitterman
American Journal of Respiratory and Critical Care…
1999
Corpus ID: 14465700
Diseases associated with pathological fibroproliferation represent a major cause of morbidity and mortality. Despite the…
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Highly Cited
1996
Highly Cited
1996
Induction of fibroblast apoptosis by anti-CD44 antibody: implications for the treatment of fibroproliferative lung disease.
C. Henke
,
P. Bitterman
,
U. Roongta
,
D. Ingbar
,
V. Polunovsky
American Journal of Pathology
1996
Corpus ID: 33271297
Fibroblast migration and proliferation within the alveolar wall and airspace after lung injury can lead to the development of…
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