fialuridine

Known as: 1-(2'fluoro-2'-deoxyarabinofuranosyl)-5-iodouracil, Fluoroiodoarauridine, 1-(2-deoxy-2-fluoro-beta-arabinofuranosyl)-5-iodouracil 
A nucleoside analog of uridine with activity against hepatitis B virus and herpes viruses. Fialuridine inhibits viral DNA polymerase and viral… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2018
05101519822018

Papers overview

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Highly Cited
2003
Highly Cited
2003
Two genetic reporter systems were developed for multimodality reporter gene imaging of different molecular-genetic processes… (More)
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Highly Cited
2003
Highly Cited
2003
New technologies are needed to characterize the migration, survival, and function of antigen-specific T cells in vivo. Here, we… (More)
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Highly Cited
2002
Highly Cited
2002
UNLABELLED The efficacy of 3 radiolabeled probes of current interest for imaging herpes simplex virus type 1 thymidine kinase… (More)
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Highly Cited
2001
Highly Cited
2001
To examine the role of the mitochondrial polymerase (Pol gamma) in clinically observed toxicity of nucleoside analogs used to… (More)
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1998
1998
Woodchucks were used to study the antiviral activity and toxicity of fialuridine (FIAU; 1,-2'deoxy-2'fluoro-1-beta-D… (More)
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1997
1997
Chronic hepatitis B is a widespread viral illness with the serious sequelae of cirrhosis and hepatocellular carcinoma. Current… (More)
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Highly Cited
1996
Highly Cited
1996
Noninvasive imaging of herpes simplex virus type 1 thymidine kinase (HSV1-tk) gene expression is possible with a clinical gamma… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND We describe severe and unexpected multisystem toxicity that occurred during a study of the antiviral nucleoside… (More)
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Highly Cited
1995
Highly Cited
1995
Imaging the expression of successful gene transduction has been demonstrated in vivo for the first time by using an appropriate… (More)
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Highly Cited
1988
Highly Cited
1988
We have developed a toxic, or suicide, vector whose action is based on the targeted expression of the herpes simplex virus 1… (More)
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