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Factors affecting the accelerated blood clearance of polyethylene glycol-liposomes upon repeated injection.
Previously, we showed that long-circulating polyethylene glycol (PEG)-liposomes are cleared rapidly from the circulation when injected repeatedly in the same animal. In this article, we describe theExpand
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Spatial Resolution and Sensitivity of the Inveon Small-Animal PET Scanner
The Inveon small-animal PET scanner is characterized by a large, 127-mm axial length and a 161-mm crystal ring diameter. The associated high sensitivity is obtained by using all lines of responseExpand
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Image-Quality Assessment for Several Positron Emitters Using the NEMA NU 4-2008 Standards in the Siemens Inveon Small-Animal PET Scanner
The positron emitters 18F, 68Ga, 124I, and 89Zr are all relevant in small-animal PET. Each of these radionuclides has different positron energies and ranges and a different fraction of single photonsExpand
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Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes.
Sterically stabilized liposomes are considered promising carriers of therapeutic agents because they can facilitate controlled release of the drugs, thereby reducing drug-related toxicity and/orExpand
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Medium-dependent regulation of proteinase gene expression in Lactococcus lactis: control of transcription initiation by specific dipeptides.
Transcriptional gene fusions with the Escherichia coli beta-glucuronidase gene (gusA) were used to study the medium- and growth-dependent expression of the divergently transcribed genes involved inExpand
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Fluorinated amino acids for tumour imaging with positron emission tomography
Abstract. The currently preferred radiopharmaceutical for positron emission tomography (PET) in oncology is 2-[18F]fluoro-deoxyglucose (FDG). Increased accumulation of this deoxyglucose analogue inExpand
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99mTc-PEG liposomes for the scintigraphic detection of infection and inflammation: clinical evaluation.
UNLABELLED Polyethyleneglycol (PEG) liposomes have been shown to be excellent vehicles for scintigraphic imaging of infection and inflammation in various experimental models. In this article weExpand
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A Novel Facile Method of Labeling Octreotide with 18F-Fluorine
Several methods have been developed to label peptides with 18F. However, in general these are laborious and require a multistep synthesis. We present a facile method based on the chelation ofExpand
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Radiolabeled liposomes for scintigraphic imaging.
Liposomes have been investigated extensively as carriers for drugs in attempts to achieve selective deposition and/or reduced toxicity. Liposomes radiolabeled with gamma emitters such as (67)Ga,Expand
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ROLE OF COMPLEMENT ACTIVATION IN HYPERSENSITIVITY REACTIONS TO DOXIL AND HYNIC PEG LIPOSOMES: EXPERIMENTAL AND CLINICAL STUDIES
ABSTRACT Pegylated liposomal doxorubicin (Doxil) and 99mTc-HYNIC PEG liposomes (HPL) were reported earlier to cause hypersensitivity reactions (HSRs) in a substantial percentage of patients treatedExpand
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