Skip to search formSkip to main contentSkip to account menu

fiacitabine

Known as: 2(1H)-pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodo-, 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine, FIAC 
A pyrimidine nucleoside analog with activity against various herpesviruses. Fiacitabine is converted to its triphosphate form in vivo and inhibits… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Antineoplastic AgentsAntiviral AgentsCytarabine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Children's descriptions of their firesetting incidents: characteristics and relationship to recidivism.
OBJECTIVE The primary purpose of the study was to identify characteristics of children's firesetting incidents and examine the… 
1992
1992
Effects of 2′‐fluorinated arabinosyl‐pyrimidine nucleosides on duck hepatitis B virus DNA level in serum and liver of chronically infected ducks
The 2′‐fluorinated arabinosyl‐pyrimidine nucleo‐ sides, 1‐(2′‐deoxy‐2′‐fluoro‐P‐D‐arabinofura‐ nosyl)‐5‐iodocytosine (FIAC) and 1… 
1990
1990
Synthesis and anti-HIV-1 activity of 2'-"up"-fluoro analogues of active anti-AIDS nucleosides 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (DDC).
1-(3-Azido-2,3-dideoxy-2-fluoro-beta-D-arabinofuranosyl)thymine (6, F-AZT) and 1-(2,3-dideoxy-2-fluoro-beta-D-threopentofuranosyl… 
1986
1986
Delayed treatment with combinations of antiviral drugs in mice infected with herpes simplex virus and application of the median effect method of analysis
Mice were inoculated intracerebrally with a lethal dose of herpes simplex virus type 2. Three days later, the mice were treated… 
Highly Cited
1984
Highly Cited
1984
Nucleosides. 129. Synthesis of antiviral nucleosides: 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracils.
Synthesis of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracils containing a vinyl (4a), 2-halovinyl (4b-d), or ethyl… 
1984
1984
The inhibition of ultraviolet radiation-induced DNA repair in human diploid fibroblasts by arabinofuranosyl nucleosides.
Highly Cited
1984
Highly Cited
1984
Inhibition of human and woodchuck hepatitis virus DNA polymerase by the triphosphates of acyclovir, 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine and E-5-(2-bromovinyl)-2…
Highly Cited
1983
Highly Cited
1983
Distribution, Metabolism, and Excretion of 1-(2-Fluoro-2-deoxy-β-d-arabinofuranosyl)thymine and 1-(2-Fluoro-2-deoxy-β-d-arabinofuranosyl)-5-iodocytosine
1-(2-Fluoro-2-deoxy-β-d-arabinofuranosyl)thymine (FMAU) and 1-(2-fluoro-2-deoxy-β-d-arabinofuranosyl)-5-iodocytosine (FIAC) are… 
1982
1982
Incorporation of metabolites of 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine into deoxyribonucleic acid of neoplastic and normal mammalian tissues.
Highly Cited
1981
Highly Cited
1981
Phospholipid derivatives of nucleoside analogs as prodrugs with enhanced catabolic stability.
The nucleoside 5'-diphosphate-L-1,2-dipalmitin derivatives of 1-beta-D-arabinofuranosylcytosine (ara-C), 9-beta-D… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)