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factor IX

Known as: Factor IX Fraction, IX Complex, Factor, thromboplastinogen B 
Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, IXa, forms a complex with factor VIII and calcium on… 
National Institutes of Health

Related topics

Related topics

44 relations
Activated Partial Thromboplastin Time measurementCoagulantsCoagulation factor IX Ag:ACnc:Pt:PPP:Qn:IACoagulation factor IX activated activity:ACnc:Pt:PPP:Qn:Coag

Narrower (24)

BeneFIXFactor IXaIB1001Kcentra

Broader (2)

Blood Coagulation FactorSerine Endopeptidases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
In vivo recovery of factor VIII and factor IX: intra‐ and interindividual variance in a clinical setting
Summary.  In vivo recovery (IVR) is traditionally used as a parameter to characterize the pharmacokinetic properties of… 
Highly Cited
1999
Highly Cited
1999
Identification of Amino Acids in the Factor XI Apple 3 Domain Required for Activation of Factor IX*
Activated coagulation factor XI (factor XIa) proteolytically cleaves its substrate, factor IX, in an interaction requiring the… 
Review
1998
Review
1998
The manufacturing process for recombinant factor IX.
Advances in recombinant DNA manufacturing technology have now made possible the production of a highly purified and active… 
Highly Cited
1995
Highly Cited
1995
Measurement of Activated Factor IX in Factor IX Concentrates: Correlation with In Vivo Thrombogenicity
Summary Current in vitro tests for thrombogenicity of FIX concentrates used for prothrombin complex concentrates (PCCs), are of… 
Highly Cited
1995
Highly Cited
1995
Role of Intron I in Expression of the Human Factor IX Gene (*)
The first intron (intron I) of the human factor IX gene, which has been previously suggested of having an expression-augmenting… 
1995
1995
Comparison of the recovery and half‐life of a high‐purity factor IX concentrate with those of a factor IX complex concentrate. Factor IX Study Group
BACKGROUND: Recovery and half‐life estimations were carried out to compare a high‐purity factor IX concentrate with an… 
Highly Cited
1989
Highly Cited
1989
Functionally important regions of the factor IX gene have a low rate of polymorphism and a high rate of mutation in the dinucleotide CpG.
We have recently described genomic amplification with transcript sequencing (GAWTS), a three-step procedure that allows direct… 
Highly Cited
1988
Highly Cited
1988
The putative factor IX gene promoter in hemophilia B Leyden.
Hemophilia B Leyden is characterized by low levels of factor IX antigen and activity before the age of 15, whereas after puberty… 
Review
1984
Review
1984
Tissue factor-dependent activation of tritium-labeled factor IX and factor X in human plasma.
Recent investigations have suggested that the activation of factor IX by factor VII/tissue factor may be an important alternative… 
Highly Cited
1973
Highly Cited
1973
Autoprothrombin II-A: Thrombin removal and mechanism of induction of fibrinolysis☆
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