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extrinsic apoptotic signaling pathway

Known as: extrinsic apoptotic pathway, extrinsic apoptotic signalling pathway 
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with… 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (2)

death-inducing signaling complex assemblyextrinsic apoptosis

Broader (1)

ovarian follicle atresia

Papers overview

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2017
2017
Oxidative imbalance and kidney damage in spontaneously hypertensive rats: activation of extrinsic apoptotic pathways.
In both humans and animals, essential hypertension acts as a risk factor for subclinical kidney damage and precedes renal… 
2016
2016
Hydroxylation of multi-walled carbon nanotubes: Enhanced biocompatibility through reduction of oxidative stress initiated cell membrane damage, cell cycle arrestment and extrinsic apoptotic pathway.
2014
2014
Viscum Album Modulates Apoptotic Related Genes in Melanoma Tumor of Mice
Cancer is a major public health problem throughout the world. It is estimated that one third of the American population will… 
Review
2012
Review
2012
State of art and recent developments of anti-cancer strategies based on TRAIL.
Multicellular organisms require apoptosis whereby the human body eliminates unnecessary and/or damaged cells. Apoptosis, or… 
2008
2008
PPAR gamma agonists can be expected to potentiate the efficacy of metronomic chemotherapy through CD36 up-regulation.
2007
2007
Arsenic trioxide induces p53-dependent apoptotic signals in myeloma cells with SiRNA-silenced p53: MAP kinase pathway is preferentially activated in cells expressing inactivated p53.
Mutations in p53 are the most common genetic abnormality in cancers. Arsenic trioxide (ATO) is an effective chemotherapeutic… 
Highly Cited
2006
Highly Cited
2006
FAS Death Domain Deletions and Cellular FADD-like Interleukin 1β Converting Enzyme Inhibitory Protein (Long) Overexpression: Alternative Mechanisms for Deregulating the Extrinsic Apoptotic Pathway in…
Purpose: Large B-cell lymphomas (LBCL) arise from normal antigen-exposed B cells at germinal center (GC) or post-GC stages of… 
2004
2004
Mitochondria in apoptosis: past, present and future
The role of mitochondria in cell death has been increasingly appreciated in the last few years and is now well established in a… 
Highly Cited
2004
Highly Cited
2004
A Dual Role of IFN-α in the Balance between Proliferation and Death of Human CD4+ T Lymphocytes during Primary Response1
Type I IFNs (IFN-αβ) enhance immune responses, notably T cell-mediated responses, in part by promoting the functional activities… 
2003
2003
Induction of tumor necrosis factor by bryostatin 1 is involved in synergistic interactions with paclitaxel in human myeloid leukemia cells.
Interactions between the protein kinase C (PKC) activator/down-regulator bryostatin 1 and paclitaxel have been examined in human… 
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