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extrinsic apoptotic signaling pathway

Known as: extrinsic apoptotic pathway, extrinsic apoptotic signalling pathway 
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with… 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (2)

death-inducing signaling complex assemblyextrinsic apoptosis

Broader (1)

ovarian follicle atresia

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Arachidonic acid activates extrinsic apoptotic pathway to enhance tumoricidal action of bleomycin against IMR-32 cells.
2017
2017
Oxidative imbalance and kidney damage in spontaneously hypertensive rats: activation of extrinsic apoptotic pathways.
In both humans and animals, essential hypertension acts as a risk factor for subclinical kidney damage and precedes renal… 
Review
2012
Review
2012
State of art and recent developments of anti-cancer strategies based on TRAIL.
Multicellular organisms require apoptosis whereby the human body eliminates unnecessary and/or damaged cells. Apoptosis, or… 
Review
2012
Review
2012
Monogenic defects in lymphocyte apoptosis
Purpose of reviewThe recognition that apoptosis – programmed cell death – is an important mechanism in immune homeostasis has led… 
2011
2011
The conservation and uniqueness of the caspase family in the basal chordate, amphioxus
BackgroundThe caspase family, which plays a central role in apoptosis in metazoans, has undergone an expansion in amphioxus… 
2008
2008
PPAR gamma agonists can be expected to potentiate the efficacy of metronomic chemotherapy through CD36 up-regulation.
2007
2007
Arsenic trioxide induces p53-dependent apoptotic signals in myeloma cells with SiRNA-silenced p53: MAP kinase pathway is preferentially activated in cells expressing inactivated p53.
Mutations in p53 are the most common genetic abnormality in cancers. Arsenic trioxide (ATO) is an effective chemotherapeutic… 
Highly Cited
2006
Highly Cited
2006
FAS Death Domain Deletions and Cellular FADD-like Interleukin 1β Converting Enzyme Inhibitory Protein (Long) Overexpression: Alternative Mechanisms for Deregulating the Extrinsic Apoptotic Pathway in…
Purpose: Large B-cell lymphomas (LBCL) arise from normal antigen-exposed B cells at germinal center (GC) or post-GC stages of… 
2004
2004
Mitochondria in apoptosis: past, present and future
The role of mitochondria in cell death has been increasingly appreciated in the last few years and is now well established in a… 
2003
2003
Induction of tumor necrosis factor by bryostatin 1 is involved in synergistic interactions with paclitaxel in human myeloid leukemia cells.
Interactions between the protein kinase C (PKC) activator/down-regulator bryostatin 1 and paclitaxel have been examined in human… 
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