death-inducing signaling complex assembly

Known as: death-inducing signalling complex assembly, DISC formation, DD-mediated complex assembly 
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
02420012017

Papers overview

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2013
2013
The prototypical death receptor Fas (also known as CD95 or Apo-1) plays an essential role in the maintenance of lymphocyte… (More)
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2013
2013
Fas binding to Fas-associated death domain (FADD) activates FADD-caspase-8 binding to form death-inducing signaling complex (DISC… (More)
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2011
2011
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising cancer therapeutic agent with cancer-selective… (More)
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Highly Cited
2008
Highly Cited
2008
Cigarette smoke-induced cell death contributes to the pathogenesis of chronic obstructive pulmonary disease, though the relative… (More)
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2008
2008
Clonal T-cell expansion in patients with T-large-granular lymphocyte (LGL) leukemia occurs by an undefined mechanism that may be… (More)
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2007
2007
We investigated the relationship between the resistance to the proapoptotic action of tumor necrosis factor-related apoptosis… (More)
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2007
2007
We investigated the relationship between the resistance to the proapoptotic action of tumor necrosis factor–related apoptosis… (More)
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Highly Cited
2005
Highly Cited
2005
Recent evidence suggests clustering of plasma membrane rafts into ceramide-enriched platforms serves as a transmembrane signaling… (More)
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2004
2004
We investigated the membrane localization of CD95 in type I and type II cells, which differ in their ability to recruit and… (More)
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2001
2001
Activation of protein kinase C (PKC) triggers cellular signals that inhibit Fas/CD95-induced cell death in Jurkat T-cells by… (More)
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