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exatecan mesylate
Known as:
(1S,9S)-1-amino-9-ethyl-5-fluoro-2,3-dihydro-9-hydroxy-4-methyl-1H,12H-benzo(de)pyrano(3',4'-6,7)indolizino(1,2-b)quinoline-10,13(9H,15H)dione methanesulfonate
, Exatecan Mesylate Hydrate
A semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by…
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National Institutes of Health
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2 relations
Narrower (1)
DX 8951f
Broader (1)
exatecan
Papers overview
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2007
2007
A phase II study of intravenous exatecan mesylate (DX-8951f) administered daily for 5 days every 3 weeks to patients with advanced ovarian, tubal or peritoneal cancer resistant to platinum, taxane…
C. Verschraegen
,
A. Kudelka
,
+6 authors
R. DeJager
Cancer Chemotherapy and Pharmacology
2007
Corpus ID: 42904332
Background: DX-8951f is a water-soluble camptothecin derivative with greater in vivo and in vitro activity than topotecan or…
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2004
2004
A phase II study of intravenous DX-8951f administered daily for five days every three weeks to patients with previously untreated metastatic gastric cancer
C. Becerra
,
C. Takimoto
,
+4 authors
R. Jagger
2004
Corpus ID: 199023626
4126 Background: Exatecan Mesylate (DX-8951f, Daiichi Pharmaceutical Co., Ltd., Japan) was synthesized to impart greater…
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