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esterastin

Known as: 5-(N-acetyl-L-asparaginyloxy)-2-hexyl-3-hydroxy- 7,10-hexadecadienoic lactone, L-Asparagine, N(2)-acetyl-, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)-3,6-dodecadienyl ester, (2S-(2alpha(1R*,3Z,6Z),3beta))- 
National Institutes of Health

Papers overview

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1994
1994
Panclicins A-E are novel and potent pancreatic lipase inhibitors produced by Streptomyces sp. NR 0619. Their structures have been… 
Highly Cited
1987
Highly Cited
1987
brane, had important effects on cellular functions1^. These inhibitors included esterastin which inhibited esterase and… 
Highly Cited
1987
Highly Cited
1987
The structure of a new pancreatic lipase inhibitor, lipstatin, produced by Streptomyces toxytricini was determined as (2S,3S,5S… 
Review
1984
Review
1984
  • H. Umezawa
  • Reviews of infectious diseases
  • 1984
  • Corpus ID: 32324606
The screening for low-molecular-weight enzyme inhibitors produced by microorganisms was initiated in 1966, and by 1972 inhibitors… 
1983
1983
The effect of a fungal metabolite, esterastin, on lysosomal acid lipase purified from rabbit liver was studied. Esterastin… 
1982
1982
The structures of ebelactone A and B, esterase inhibitors produced by Streptomyces sp. MG7-G1 strain, have been determined to be… 
Review
1980
Review
1980
  • H. Umezawa
  • Recent results in cancer research. Fortschritte…
  • 1980
  • Corpus ID: 36397571
Microorganisms are the treasury of organic compounds which have various structures and various biologic and medicinal activities… 
1980
1980
Sir: We have demonstrated that aminopeptidases, phosphatases and esterases are located not only in cells but also on the cellular… 
Highly Cited
1978
Highly Cited
1978
Sir: Recently we demonstrated that activities of aminopeptidases and alkaline phosphatase were located on the surface of various… 
1978
1978
Esterastin (1) is obtained as a colorless powder, mip 99-100•Ž; [ƒ¿]23D+1l•‹ (c 1, CHCI3); UV 265 nm (sh) in 95 % aqueous…