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esterastin

Known as: 5-(N-acetyl-L-asparaginyloxy)-2-hexyl-3-hydroxy- 7,10-hexadecadienoic lactone, L-Asparagine, N(2)-acetyl-, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)-3,6-dodecadienyl ester, (2S-(2alpha(1R*,3Z,6Z),3beta))- 
 
National Institutes of Health

Papers overview

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1994
1994
Panclicins A-E are novel and potent pancreatic lipase inhibitors produced by Streptomyces sp. NR 0619. Their structures have been… Expand
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1989
1989
Rabbit aortic smooth muscle cells in culture were incubated with 0.04-500 M esterastin. Acid cholesteryl ester hydrolase (ACEH… Expand
Highly Cited
1987
Highly Cited
1987
The structure of a new pancreatic lipase inhibitor, lipstatin, produced by Streptomyces toxytricini was determined as (2S,3S,5S… Expand
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Highly Cited
1987
Highly Cited
1987
brane, had important effects on cellular functions1^. These inhibitors included esterastin which inhibited esterase and… Expand
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1983
1983
The effect of a fungal metabolite, esterastin, on lysosomal acid lipase purified from rabbit liver was studied. Esterastin… Expand
1982
1982
The structures of ebelactone A and B, esterase inhibitors produced by Streptomyces sp. MG7-G1 strain, have been determined to be… Expand
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1981
1981
We have been searching for enzyme inhibitors in culture filtrates of microbes and have found leupeptin, antipain, chymostatin… Expand
1980
1980
Sir: We have demonstrated that aminopeptidases, phosphatases and esterases are located not only in cells but also on the cellular… Expand
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1978
1978
Esterastin (1) is obtained as a colorless powder, mip 99-100•Ž; [ƒ¿]23D+1l•‹ (c 1, CHCI3); UV 265 nm (sh) in 95 % aqueous… Expand
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Highly Cited
1978
Highly Cited
1978