Skip to search formSkip to main contentSkip to account menu

eplerenone

Known as: eplerenon, 9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester, eplerenone [Chemical/Ingredient] 
A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby… 
National Institutes of Health

Related topics

Related topics

13 relations
Arterial Vasodilation [PE]Decreased Blood Pressure [PE]Diabetes Mellitus, Non-Insulin-DependentHypertensive disease

Narrower (1)

Inspra

Broader (2)

Mineralocorticoid Receptor AntagonistsSpironolactone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
New Stability Indicating Liquid Chromatographic Method for the Determination of Eplerenone in the Presence of Internal Standard
Introduction: A simple stability indicating reverse-phase high-performance liquid chromatographic (RP-HPLC) method has been… 
2016
2016
ENVIRONMENTALLY FRIENDLY LC/MS DETERMINATION OF EPLERENONE IN HUMAN PLASMA.
Eplerenone (EPL), a selective aldosterone receptor antagonist, is indicated in the treatment of chronic heart failure and… 
2013
2013
PREPARATION AND IN VITRO EVALUATION OF CHITOSAN MICROSPHERES OF EPLERENONE
Objective: To develop and evaluate Eplerenone (EP) microspheres using natural polymer like Chitosan. Eplerenone is a suitable… 
2012
2012
Development and Validation of Gradient RP-HPLC for Estimation of Impurities in Eplerenone Tablet dosage form
A simple reverse phase gradient HPLC method used for simultaneous identification of Eplerenone impurities in market tablet dosage… 
2011
2011
Aldosterone antagonists--last man standing?
The transformation of cardiac care over the past half century has been breathtaking to witness. In large part, this… 
2011
2011
Eplerenone in mild heart failure.
1. Department of Health and Human Services. OPTN/SRTR annual report 2009. (http://optn.transplant.hrsa.gov/ar2009.) 2. Haynes L… 
2011
2011
Co-prescription of co-trimoxazole and spironolactone in elderly patients
The combination should be used with caution because of the risk of hyperkalaemia 
2010
2010
Heart failure: Placing an EMPHASIS on the mineralocorticoid receptor—benefit of eplerenone in mild HF
Heart failure: Placing an EMPHASIS on the mineralocorticoid receptor—benefit of eplerenone in mild HF 
Review
2005
Review
2005
Aldosterone receptor antagonists in the medical management of chronic heart failure.
The benefits of aldosterone receptor antagonists (spironolactone and eplerenone) for patients with heart failure were shown in 2… 
2000
2000
Absorption and Disposition of a Selective Aldosterone Receptor Antagonist, Eplerenone, in the Dog
AbstractPurpose. The present study was conducted to characterize the pharmacokinetics of eplerenone (EP), a selective aldosterone… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)