Mineralocorticoid Receptor Antagonists

Known as: Mineralocorticoid Antagonists, Receptor Antagonists, Mineralocorticoid, Aldosterone Receptor Antagonist 
A class of agents that act by selectively inhibiting aldosterone receptor activation with diuretic activity. Aldosterone receptor antagonists bind to… (More)
National Institutes of Health

Papers overview

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2015
2015
OBJECTIVES This study aimed to evaluate the specific role of the 2 available mineralocorticoid receptor antagonists (MRAs… (More)
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Review
2013
Review
2013
Spironolactone was first developed over 50 years ago as a potent mineralocorticoid receptor (MR) antagonist with undesirable side… (More)
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Review
2012
Review
2012
Mineralocorticoid receptor antagonists (MRAs) improve survival and reduce morbidity in patients with heart failure, reduced… (More)
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Review
2009
Review
2009
BACKGROUND Treatment with angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB) is increasingly… (More)
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Highly Cited
2007
Highly Cited
2007
Exposure to excess aldosterone results in cardiac damage in hypertensive states. We evaluated the long-term cardiac structural… (More)
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Highly Cited
2006
Highly Cited
2006
Studies have shown that dual therapy with angiotensin-converting enzyme inhibitors (ACEI) and either angiotensin II receptor… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Experimental evidence suggests that aldosterone may contribute to progressive kidney disease. Although angiotensin… (More)
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Review
2005
Review
2005
Hypertension in blacks is more prevalent and less often controlled than the hypertension of other ethnic groups. We sought to… (More)
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2004
2004
Aldosterone can elicit rapid nongenomic effects both in vivo and in vitro, often mediated by signal transduction cascades… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Aldosterone has been implicated in the effects of angiotensin II in the vasculature. We hypothesized that there is… (More)
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