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Mineralocorticoid Receptor Antagonists

Known as: Mineralocorticoid Antagonists, Receptor Antagonists, Mineralocorticoid, Aldosterone Receptor Antagonist 
A class of agents that act by selectively inhibiting aldosterone receptor activation with diuretic activity. Aldosterone receptor antagonists bind to… 
National Institutes of Health

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Aldosterone AntagonistsCanrenoic AcidCanrenoneRU 28318
In BloodMineralocorticoid Receptor Antagonists [MoA]aspects of radiation effectschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Aldosterone antagonists for preventing the progression of chronic kidney disease.
BACKGROUND Treatment with angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB) is increasingly… 
Review
2007
Review
2007
Novel therapies blocking the renin–angiotensin–aldosterone system in the management of hypertension and related disorders
Although significant advances have been made in the therapeutic blockade of the renin–angiotensin–aldosterone system (RAAS) using… 
2006
2006
Mitigation of radiation nephropathy after internal alpha-particle irradiation of kidneys.
PURPOSE Internal irradiation of kidneys as a consequence of radioimmunotherapy, radiation accidents, or nuclear terrorism can… 
Review
2004
Review
2004
Aldosterone-induced vasculopathy
Review
2003
Review
2003
RAAS escape: A real clinical entity that may be important in the progression of cardiovascular and renal disease
Interruption of the renin-angiotensin-aldosterone system (RAAS) at different levels is target-organ protective in several disease… 
2003
2003
Spironolactone prevents cardiac collagen proliferation after myocardial infarction in rats
1. Aldosterone has been considered a key hormone in the regulation of water, sodium and potassium metabolism, thus influencing… 
Review
2003
Review
2003
Aldosterone as a target in congestive heart failure.
Highly Cited
2002
Highly Cited
2002
Appraisal of the role of angiotensin II and aldosterone in ventricular myocyte apoptosis in adult normotensive rat.
Despite previous observations on isolated ventricular myocytes, there are still few evidences that angiotensin II induces… 
1995
1995
The two faces of a steroid antagonist: When an antagonist isn't
1986
1986
Hypercalciuria of mineralocorticoid escape: clearance and micropuncture studies in the rat.
Chronic mineralocorticoid excess results in the predicted retention of salt and water followed by a period of escape from sodium… 
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