Canrenone

Known as: Aldadiene, Canrenone [Chemical/Ingredient], Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, gamma-lactone, (17alpha)- 
An aldosterone antagonist with potassium-sparing diuretic activity. Canrenone specifically antagonizes aldosterone at the mineralocorticoid receptor… (More)
National Institutes of Health

Papers overview

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2014
2014
Canrenone is a derivative of spironolactone with lower antiandrogen activity. The drug is used only in few countries and can… (More)
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2009
2009
AIMS To test whether canrenone, an aldosterone receptor antagonist, improves left ventricular (LV) remodelling in NYHA class II… (More)
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2002
2002
BACKGROUND A case of digoxin toxicity resulted from falsely low values with the MEIA II assay for digoxin (AxSYM; Abbott). The… (More)
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1999
1999
Canrenone and spironolactone caused falsely low readings in a common assay for digoxin (AxSym MEIA) due to negative cross… (More)
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1990
1990
Canrenone, a metabolic product of spironolactone, which competes with ouabain for binding to Na-K-ATPase at the digitalis… (More)
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1990
1990
Although current immunoassay kits for digoxin supposedly have antibodies of high specificity, serum digoxin levels in patients… (More)
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1981
1981
Canrenone, a spironolactone metabolite, was tested for its possible effects on (Na+-K+) adenosine triphosphatase (ATPase… (More)
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1977
1977
The influence of food intake on the bioavailability of canrenone, the major and active metabolite of spironolactone, was explored… (More)
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1976
1976
Effects of spironolactone, canrenone and canrenoate-K on adrenal cytochrome P450 (P450) and corticosteroid biosynthesis were… (More)
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1974
1974
The metabolic conversion of spironolactone (I) to canrenone (II) was investigated using a chemical model reaction by treatment of… (More)
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