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epibatidine

Known as: 7-Azabicyclo(2.2.1)heptane, 2-(6-chloro-3-pyridinyl)-, exo- 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (4)

Analgesics, Non-NarcoticBridged Bicyclo Compounds, HeterocyclicNicotinic AgonistsPyridines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
PD14-03 ACTIVATION OF BRAIN NICOTINIC ACETYLCHOLINE RECEPTORS CAN SUPPRESS MICTURITION REFLEX IN RATS
INTRODUCTION AND OBJECTIVES: Psychological stress exacerbates symptoms of bladder dysfunction. We previously reported that… 
2017
2017
A possible desensitized state conformation of the human α7 nicotinic receptor: A molecular dynamics study.
2017
2017
Plasticity in Brainstem Mechanisms of Pain Modulation by Nicotinic Acetylcholine Receptors in the Rat
Visual Abstract Individuals with chronic pain may be driven to smoke more because the analgesic efficacy of nicotine diminishes… 
2009
2009
Activation and desensitization of α3β4 rat neuronal nicotinic receptors: Role of negatively charged amino acids in β4 F-loop
320 The nAChR-subunit topology is common for all other pentameric neurotransmitter receptor channels. These ionic channels… 
2007
2007
Desensitized nicotinic receptors that, however, afford cytoprotection in bovine chromaffin cells
Neuronal nicotinic receptors for acetylcholine (nAChRs) are among the ionotropic receptors that suffer the most desensitization… 
2007
2007
Engineered site-directed labeling of nicotinic acetylcholine receptors using reactive epibatidine derivatives
We developed an engineered site-directed labeling method (Foucaud et al., 2001) to investigate ligand receptor interactions on… 
2005
2005
The Dorsal Raphe Nucleus as a Site of Action of the Antinociceptive and Behavioral Effects of the α4 Nicotinic Receptor Agonist Epibatidine
The mechanisms and sites of action of epibatidine-induced antinociception and side effects are poorly understood. The present… 
2002
2002
Increased high-affinity nicotinic receptor-binding in rats exposed to lead during development.
Review
1997
Review
1997
IPH , an Epibatidine Analog , Binds with High Affinity to Neuronal Nicotinic Cholinergic Receptors 1
An analog of epibatidine (EB) was synthesized with an iodine atom in the 2 position of the pyridyl ring. This analog, (6)-exo2-(2… 
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