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emtricitabine

Known as: 4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one, Emtricitabinum, (-)-cis-4-amino-5-Fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one 
A synthetic fluoro derivative of thiacytidine with potent antiviral activity. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate… 
National Institutes of Health

Related topics

Related topics

28 relations

Broader (3)

Anti-HIV AgentsAntiviral AgentsReverse Transcriptase Inhibitors

Narrower (8)

AtriplaBW 524W91CompleraCoviracil
Emtricitabine:Susc:Pt:Isolate:OrdQn:PhenotypingHIV InfectionsIn BloodLamivudine or Emtricitabine:Susc:Pt:Isolate:OrdQn:Genotyping

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
PrEP implementation: moving from trials to policy and practice
It is increasingly clear that the HIV response will not be sustainable if the number of infections is not significantly reduced. 
2014
2014
French 2013 guidelines for antiretroviral therapy of HIV-1 infection in adults
These guidelines are part of the French Experts’ recommendations for the management of people living with HIV/AIDS, which were… 
Review
2013
Review
2013
A review of nanotechnological approaches for the prophylaxis of HIV/AIDS.
Highly Cited
2008
Highly Cited
2008
Quantification of seven nucleoside/nucleotide reverse transcriptase inhibitors in human plasma by high-performance liquid chromatography with tandem mass-spectrometry.
Highly Cited
2003
Highly Cited
2003
Economic evaluation of galantamine in the treatment of mild to moderate Alzheimer's disease in the United States.
2003
2003
Assessment of oral bioavailability enhancing approaches for SB-247083 using flow-through cell dissolution testing as one of the screens.
Highly Cited
2000
Highly Cited
2000
Evaluation of N-succinyl-chitosan as a systemic long-circulating polymer.
1997
1997
Structure-activity relationships of 2'-deoxy-2',2'-difluoro-L-erythro-pentofuranosyl nucleosides.
Following the recent discoveries that some L-nucleosides are more or equal potent than their D-counterparts, we synthesized 2… 
Highly Cited
1992
Highly Cited
1992
Enzyme-mediated enantioselective preparation of pure enantiomers of the antiviral agent 2',3'-dideoxy-5-fluoro-3'-thiacytidine (FTC) and related compounds
Racemic 2',3'-dideoxy-3'-thianucleosides were resolved by enzyme-catalyzed hydrolysis of their butyrate ester derivatives 
1964
1964
Synthesis of pyrimidin-2-one deoxyribosides and their ability to support the growth of the deoxyriboside-requiring organism Lactobacillus acidophilus R 26.
In the past, several methods for reducing pyrimidine nucleosides and nucleotides have been described. Levene & LaForge (1912… 
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