emtricitabine

Known as: 4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one, Emtricitabinum, (-)-cis-4-amino-5-Fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one 
A synthetic fluoro derivative of thiacytidine with potent antiviral activity. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Drug concentrations associated with protection from HIV-1 acquisition have not been determined. We evaluated drug concentrations… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Antiretroviral preexposure prophylaxis is a promising approach for preventing human immunodeficiency virus type 1 (HIV… (More)
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Highly Cited
2012
Highly Cited
2012
Highly Cited
2012
BACKGROUND Preexposure prophylaxis with antiretroviral agents has been shown to reduce the transmission of human immunodeficiency… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND The HIV integrase strand transfer inhibitor elvitegravir (EVG) has been co-formulated with the CYP3A4 inhibitor… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Efavirenz with tenofovir-disoproxil-fumarate and emtricitabine is a preferred antiretroviral regimen for treatment… (More)
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Highly Cited
2011
Highly Cited
2011
A mainstay of strategies to prevent HIV-1 transmission is to use antiretroviral therapy (ART) for pre-exposure prophylaxis (PrEP… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Abacavir-lamivudine and tenofovir DF-emtricitabine fixed-dose combinations are commonly used as first-line… (More)
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Highly Cited
2009
Highly Cited
2009
The 2009 update of the American Association for the Study of Liver Diseases (AASLD) Practice Guidelines for Management of Chronic… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Atazanavir/ritonavir is as effective as lopinavir/ritonavir, with a more favourable lipid profile and less… (More)
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