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efinaconazole

Known as: (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol, (2R,3R)-2-(2,4-difluorofenil)-3-(4-metilenopiperidin-1-il)-1-(1h-1,2,4-triazin-1-il)butan-2-ol 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Antifungal AgentsTriazoles
AzolesMycoses

Narrower (2)

JubliaKP 103

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Onychomycosis: a review
Onychomycosis is a fungal infection of the nail, causing discoloration and thickening of the affected nail plate, and is the most… 
2019
2019
Efficacy of long‐term treatment with efinaconazole 10% solution in patients with onychomycosis, including severe cases: A multicenter, single‐arm study
We evaluated the efficacy of efinaconazole 10% topical solution in long‐term use, for up to 72 weeks, for onychomycosis… 
2018
2018
In Vitro Antifungal Activity of Novel Triazole Efinaconazole and Five Comparators against Dermatophyte Isolates
ABSTRACT The objective of this study was to assess the in vitro activity of the novel triazole antifungal drug, efinaconazole… 
Review
2017
Review
2017
Onychomycosis in the 21st Century: An Update on Diagnosis, Epidemiology, and Treatment
Onychomycosis accounts for 50% of all nail disease cases and is commonly caused by dermatophytes. Diabetes, human… 
2016
2016
Application of Hansen Solubility Parameters to predict drug-nail interactions, which can assist the design of nail medicines.
Review
2015
Review
2015
Triazole antifungals: a review.
Invasive fungal infections and systemic mycosis, whether from nosocomial infection or immunodeficiency, have been on an upward… 
2015
2015
Efinaconazole topical solution, 10%: the benefits of treating onychomycosis early.
OBJECTIVE To evaluate efficacy of efinaconazole topical solution, 10% in onychomycosis patients with early and long-standing… 
Highly Cited
2014
Highly Cited
2014
The Low Keratin Affinity of Efinaconazole Contributes to Its Nail Penetration and Fungicidal Activity in Topical Onychomycosis Treatment
ABSTRACT Onychomycosis is a common fungal nail disease that is difficult to treat topically due to the deep location of the… 
Review
2013
Review
2013
Comparison of In Vitro Antifungal Activities of Efinaconazole and Currently Available Antifungal Agents against a Variety of Pathogenic Fungi Associated with Onychomycosis
ABSTRACT Onychomycosis is a common fungal nail infection in adults that is difficult to treat. The in vitro antifungal activity… 
Highly Cited
2013
Highly Cited
2013
Mechanism of Action of Efinaconazole, a Novel Triazole Antifungal Agent
ABSTRACT The mechanism of action of efinaconazole, a new triazole antifungal, was investigated with Trichophyton mentagrophytes… 
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