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edema factor

 
National Institutes of Health

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Review
2007
Review
2007
Anthrax toxin consists of three nontoxic proteins that self-assemble at the surface of receptor-bearing mammalian cells or in… Expand
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Highly Cited
2006
Highly Cited
2006
The pathogenesis of Bacillus anthracis, the bacterium that causes anthrax, depends on secretion of three factors that combine to… Expand
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Highly Cited
2005
Highly Cited
2005
Edema factor (EF), a key anthrax exotoxin, has an anthrax protective antigen‐binding domain (PABD) and a calmodulin (CaM… Expand
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Highly Cited
2004
Highly Cited
2004
The two enzymatic components of anthrax toxin, lethal factor (LF) and edema factor (EF), are transported to the cytosol of… Expand
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Highly Cited
2004
Highly Cited
2004
Edema factor (EF), a key virulence factor in anthrax pathogenesis, has calmodulin (CaM)-activated adenylyl cyclase activity. We… Expand
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Highly Cited
2004
Highly Cited
2004
The protective antigen (PA) of anthrax toxin binds to a cell surface receptor, undergoes heptamerization, and binds the enzymatic… Expand
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Highly Cited
2002
Highly Cited
2002
The three proteins that comprise anthrax toxin, edema factor (EF), lethal factor (LF), and protective antigen (PA), assemble at… Expand
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Highly Cited
2002
Highly Cited
2002
Assembly of anthrax toxin complexes at the mammalian cell surface involves competitive binding of the edema factor (EF) and… Expand
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Highly Cited
1994
Highly Cited
1994
The protective antigen component (PA) of anthrax toxin binds to receptors on target cells and conveys the toxin's edema factor… Expand
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Highly Cited
1982
Highly Cited
1982
  • S. Leppla
  • Proceedings of the National Academy of Sciences…
  • 1982
  • Corpus ID: 20307576
Anthrax toxin is composed of three proteins: protective antigen (PA), lethal factor (LF), and edema factor (EF). These proteins… Expand
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